Abstract Library

#3896 Diagnostic utility of menin immunohistochemistry in MEN1 syndrome patients

Introduction: A clinical diagnosis of Multiple Neoplasia type 1 (MEN1) syndrome is confirmed with genetic testing. It is expected that menin protein expression is lost in MEN1 related tumors.

Conference:

Presenting Author: Verschuur A

Authors: Verschuur A, Kok A, Morsink F, de Leng W, van den Broek M,

Keywords: MEN1, MEN1 syndrome, parathyroid, parathyroid adenoma, menin, immunohistochemistry,

#3465 Opposite treatment approach in two institutes identifies primary tumor resection to be associated with improved disease specific mortality in patients with stage IV small intestinal neuroendocrine tumors (SI-NET) vs watch-and-wait strategy

Introduction: SI-NET often present with metastatic disease. There is an ongoing debate whether or not to perform primary tumor resection (PTR) in stage IV SI-NET.

Conference:

Presenting Author: Levy S

Authors: Levy S, Arthur J, Banks M, Kok N, Fenwick S,

Keywords: SI-NET, surgical approach, stage 4, instrumental variable,

#3049 Organoid Models of Neuroendocrine Cell Growth and Tumorigenesis

Introduction: A paucity of in vitro and in vivo models has limited the study of Neuroendocrine neoplasms (NENs). Moreover, little is known about normal neuroendocrine (NE) cells and how they contribute to NEN formation.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Dayton T, Den Hartigh L, Levy S, van den Berg J, Kok N,

Keywords: Organoids, NENs, pulmonary neuroendocrine cells,