Abstract Library

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#1709 68Ga-NODAGA-exendin-4 PET/CT for the Localization of Insulinomas: Preliminary Data from a Prospective Multicenter Imaging Study.

Introduction: Insulinomas are usually small, single tumors. Precise preoperative localization of the tumor is essential. Imaging techniques like CT and MRI have limited sensitivity and also somatostatin receptor (SSTR) imaging is not specific. Exendin specifically binds the GLP-1 receptor (GLP-1R), which is markedly upregulated in insulinomas. 68Ga-DOTA-exendin-4 PET/CT has been shown to be feasible in detecting insulinomas. Replacing DOTA by NODAGA ensures higher specific activities. We propose 68Ga-NODAGA-exendin-4 PET/CT as a promising new method for improved localization of insulinomas.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: Boss M

Authors: Boss M, Buitinga M, Brom M, Wild D, Prasad V,

Keywords: Insulinoma, PET, exendin,

#1101 Malignant Insulinoma in a Patient with Diabetes: Response to Treatment and a Return to Insulin Injections

Introduction: A 64 year old male with a fourteen year history of diabetes had been treated with insulin for eight years. Over a four week period he noticed that his insulin requirements were reducing and he experienced episodes of symptomatic hypoglycaemia and upper abdominal pain. Following referral a CT scan was performed which revealed numerous liver metastases and a 8.4 by 5.2 cm mass replacing the pancreas. Liver biopsy diagnosed a neuroendocrine tumour with a MIB-1 index of up to 18%. The tumour was somatostatin receptor positive as evidenced by an octreotide scan.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author: Sherriff D

Authors: Sherriff D, Drake B,

Keywords: insulinoma, diabetes, prrt,

#71 Treatment of unresectable neuroendocrine liver tumors with Y-90 microsphere

Introduction: The primary therapy of liver lesions of NET is surgery but it is most possible for all patients. Selective internal radiation therapy (SIRT) is a newly available method to treats liver metastases.

Conference: 7th Annual ENETSConcerence (2010)

Presenting Author: Kucuk O

Authors: Kucuk O, Lacin S, Oz I, Bilgic S,

Keywords: 90Y, liver NETS, intra-arterial radionuclide treatment,