Abstract Library

#3748 Association of MINEN with GIST on neurofibromatosis – A case report

Introduction: Although most digestive neuroendocrine tumors (NETs) are sporadic, around 5% of NETs occur in a context of hereditary predisposition, mainly type 1 multiple endocrine neoplasia (NEM1) and Von Hippel-Lindau disease (VHL).

Conference:

Presenting Author:

Authors: Samia K, Fatima H, Nabil B, Benali T, Aisha B,

Keywords: NEN, GIST, MINEN, DOG1,

#3526 Neurofibromatosis type 1 in combination with Pheochromocytoma (clinical case)

Introduction: Neurofibromatosis type 1 (NF-1) is a rare disease with characteristic pathological changes of the skin and nervous system, often in combination with abnormalities of other organs and systems. Endocrine neoplasms such as pheochromocytoma/paraganglioma, gastroenteropancreatic neuroendocrine tumors, thyroid tumors, and adrenal tumors, can also be rarely associated with NF-1.

Conference:

Presenting Author: Motrenko A

Authors: Motrenko A, Britvin T, Ilovayskaya I, Gurevich L,

Keywords: Neurofibromatos, pheochromocytoma, metanerins,

#1870 Detection of Metastatic Insulinoma with 68Ga-NODAGA-Exendin-4 PET/CT in a Young Child – A Case Report

Introduction: Malignant insulinomas are extremely rare in children. Localizing metastases of insulinoma is challenging. Imaging modalities like CT and MRI show limited results. Somatostatin-receptor (SSTR) imaging (SRS) performs better. However, a subgroup of malignant insulinoma lack SSRT-2 and can, therefore, not be localized using SRS. We propose that in these cases GLP-1R imaging, using the stable GLP-1 analog exendin, could play an important role.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: Boss M

Authors: Boss M, de Herder W, Hussain K, Shah P, Brom M,

Keywords: Metastatic insulinoma, GLP-1R, PET, exendin,

#1709 68Ga-NODAGA-exendin-4 PET/CT for the Localization of Insulinomas: Preliminary Data from a Prospective Multicenter Imaging Study.

Introduction: Insulinomas are usually small, single tumors. Precise preoperative localization of the tumor is essential. Imaging techniques like CT and MRI have limited sensitivity and also somatostatin receptor (SSTR) imaging is not specific. Exendin specifically binds the GLP-1 receptor (GLP-1R), which is markedly upregulated in insulinomas. 68Ga-DOTA-exendin-4 PET/CT has been shown to be feasible in detecting insulinomas. Replacing DOTA by NODAGA ensures higher specific activities. We propose 68Ga-NODAGA-exendin-4 PET/CT as a promising new method for improved localization of insulinomas.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: Boss M

Authors: Boss M, Buitinga M, Brom M, Wild D, Prasad V,

Keywords: Insulinoma, PET, exendin,

#1055 Neuroendocrine Pancreatic Tumor Associated with a Cerebral Neurofibroma. A Case Report.

Introduction: Neuroendocrine pancreatic tumors (pNET) are rare in young patients. They usually occur in the setting of genetic syndromes.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author: Lico V

Authors: Moletta L, Milanetto A, Lico V, Farinati F, Alaggio R,

Keywords: pnet, cerebral neurofibroma, nf-1,