Abstract Library
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#2700 Pancreatic Neuroendocrine Neoplasms and Liver Metastases: When Size Matters
Introduction: Small non-functioning pNENs are low grade indolent tumors, however distant metastases have also been documented in this subset of patients
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author:
Authors: Monteleone M, Rossi R, Altomare M, Prinzi N, Cattaneo L,
Keywords: Pancreatic neuroendocrine neoplasia, Liver metastases,
Introduction: Neuroendocrine tumors (NET) of the pancreas represent a rare entity of primary pancreatic tumors. However, with the continuous progress in modern diagnostics NET`s are increasingly detected and prognostic factors are being reevaluated to establish personalized treatment concepts.
Conference: 14th Annual ENETSConcerence (2017)
Presenting Author:
Authors: Klein F, Bahra M, Pratschke J, Pavel M, Pape U,
Introduction: The ENETS guidelines classify Gastroenteropancreatic Neuroendocrine Tumours (GEP NETs) according to the histological assessment of tumour mitotic count or Ki67 labelling index (LI) on paraffin-embedded tissue, because proliferation rate has been shown to strongly correlate with prognosis. Since the guidelines were published, Ki67 has been established as the more reproducible measure, and further large case series have been reported.
Conference: 12th Annual ENETSConcerence (2015)
Presenting Author: Cave J
Authors: Richards-Taylor S, Tilley C, Hu J, Pearce N, Armstrong T,
Introduction: A 64 year old male with a fourteen year history of diabetes had been treated with insulin for eight years. Over a four week period he noticed that his insulin requirements were reducing and he experienced episodes of symptomatic hypoglycaemia and upper abdominal pain. Following referral a CT scan was performed which revealed numerous liver metastases and a 8.4 by 5.2 cm mass replacing the pancreas. Liver biopsy diagnosed a neuroendocrine tumour with a MIB-1 index of up to 18%. The tumour was somatostatin receptor positive as evidenced by an octreotide scan.
Conference: 12th Annual ENETSConcerence (2015)
Presenting Author: Sherriff D
Authors: Sherriff D, Drake B,
Keywords: insulinoma, diabetes, prrt,
Introduction: Cytokeratin 19 (CK19) is the marker of pluripotent cells of the epithelium of the pancreatic ducts, which is not detected in differentiated endocrine cells. Our experience shows that many patients with neuroendocrine tumors of the pancreas (pNET) G2 have a rapid progression of the disease a few years after diagnosis, and metastases are found most commonly in the liver.
Conference: 11th Annual ENETSConcerence (2014)
Presenting Author:
Authors: Gurevich L, Korsakova N, Kazantseva I, Egorov A, Britvin T,
Keywords: pancreas, neuroendocrine tumors, risk factors, Ki-67, cytokeratin 19,