Abstract Library

#4240 Plasma extracellular vesicles number and size distinguish patients with neuroendocrine neoplasms

Introduction: Neuroendocrine Neoplasms (NENs) are heterogeneous neoplasms, whose metastatic potential is challenging to predict. Extracellular vesicles (EVs) have been described as mediators of communication between the tumor cells and their microenvironment, driving the formation of metastatic niches.

Conference:

Presenting Author: Angelioudaki I

Authors: Angelioudaki I, Pantazatou V, Tzingounis A, Kataki A, Memos N,

Keywords: Extracellular vesicles, plasma, Gastroenteropancreatic NEN,

#3975 Patterns of radiotracer uptake in patients with resectable lung carcinoids undergoing preoperative functional imaging

Introduction: There is paucity of real-world data on the use of preoperative functional imaging (PFI) in patients (pts) with lung carcinoids (LC), and the association of radiotracer uptake (RU) with histology/outcomes.

Conference:

Presenting Author: Diamantopoulos L

Authors: Diamantopoulos L, Dimou A, Parikh K, Shanshal M, Schwecke A,

Keywords: carcinoid, lung, gallium, pet, somatostatin,

#3932 Artisan: Prospective phase II trial of TheraSphere Selective Internal Radiation Therapy (SIRT) for liver metastases in neuroendocrine tumors (NETs)

Introduction: The liver is the commonest site of metastases and is an independent predictor of poor outcome. SIRT allows delivery of high dose radiation to liver metastases and has shown promise in the management of NETs. We determined the safety and efficacy of SIRT in those with inoperable liver metastases in a prospective study.

Conference:

Presenting Author: Ahmed Q

Authors: Ahmed Q, Doumanoglou N, Evans J, Martinez M, Ward C,

Keywords: radioembolization, carcinoid, neuroendocrine, metastases,

#3762 Cabozantinib in high grade neuroendocrine neoplasms – Interim results from a Phase II trial

Introduction: Patients with high grade neuroendocrine neoplasms (HG-NENs) have limited treatment options. Cabozantinib, a multi kinase inhibitor can affect tumor growth and metastasis.

Conference:

Presenting Author: Trikalinos N

Authors: Trikalinos N, Pedersen K, Tan B, Amin M, Rama S,

Keywords: Cabozantinib, high-grade, neuroendocrine, neoplasm, clinical trial,

#3761 Tuberous sclerosis (TSC) mutations in patients with pancreatic neuroendocrine neoplasms are associated with distinct pathological, radiological and treatment-related findings

Introduction: Patients with pancreatic neuroendocrine neoplasms (PanNENs) can rarely harbour tuberous sclerosis (TSC) mutations but there is no knowledge on the pathological, radiological or treatment-related associations of those.

Conference:

Presenting Author: Navale P

Authors: Navale P, Itani M, Trikalinos N,

Keywords: TSC, temozolomide, oncocytic, PanNEN,