Abstract Library

#2789 The Patient Journey – Experience from Symptoms to Diagnosis among Patients with Small Intestinal Neuroendocrine Tumours (SINET)

Introduction: Patients with SINET often have diffuse symptoms delaying diagnosis. In a patient survey it was observed that 1/3 of NET patients had a time span to diagnosis of > 5 years, with a median of 52 months. Here we assess the patients’ experience during that time period.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Holgersson K

Authors: Holgersson K, Ståhl E, Nilsson M, Grauers B, Mårtensson-Djäken E,

Keywords: SINET, patients' experience, interview,

#672 Affinity Proteomic Plasma Analysis of Human Well-Differentiated Small Intestinal Neuroendocrine Tumors

Introduction: Small intestine neuroendocrine tumor (SI-NET) patients get diagnosis at the stage of metastasis and there is a lack of curative treatments.

Conference: 10th Annual ENETSConcerence (2013)

Presenting Author: Giandomenico V

Authors: Darmanis S, Cui T, Li S, Öberg K, Nilsson P,

Keywords: small intestine neuroendocrine tumors, blood, antibody-suspension bead-array, biomarker,

#119 Valproic acid induces apoptosis-mediated cell death of the ileal carcinoid cell line GOT1

Introduction: Downregulation of tumor suppressor genes, evasion from apoptosis, and reduced differentiation are hallmarks of cancer that can be due to abnormal epigenetic control. Histone deacetylase (HDAC) is an enzyme involved in the deacetylation of histone proteins, resulting in chromatin remodelling and altered gene transcription. HDAC inhibitors are emerging as useful anticancer drugs.

Conference: 7th Annual ENETSConcerence (2010)

Presenting Author:

Authors: Arvidsson Y, Ahlman H, Nilsson O,

Keywords: carcinoid, HDAC, apoptosis, valproic acid,