Abstract Library
Members may log into MY ENETS to visit the abstract library from previous ENETS conferences.
Participants of the ENETS Conference in 2024 can now access the abstract booklet, e-posters and videos, slide decks of talks, the poster carousel, and more via My ENETS.
ENETS Abstract Search
#3053 The Splicing Machinery Is Dysregulated in Low Grade Pulmonary Neuroendocrine Tumors
Introduction: Alternative splicing dysregulation is increasingly regarded as a novel cancer hallmark influencing all key tumor features. We have shown that neuroendocrine tumors (NETs) overexpress aberrantly spliced variants of neuropeptides and receptors that increase tumor malignancy. More recently, we discovered that the splicing machinery is dysregulated in pituitary and pancreatic NETs. To date, the status of this machinery in low grade pulmonary NETs is largely unknown.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author: Blázquez-Encinas R
Authors: Blázquez-Encinas R, Caro M, Pedraza-Arévalo S, Alors-Pérez E, Herrera-Martínez A,
Keywords: low grade pulmonary NETs, splicing, splicing machinery, malignancy,
Introduction: Adrenocortical carcinoma (ACC) in adults is a rare tumor (incidence 0.7-2/1000000/year). Median overall survival is 3-4 years and five-year survival is 0-28% in metastatic disease. The only curative therapy is complete surgical resection, plus adjuvant therapy depending on poor prognostic factors (ENSAT stage III, R1 resection or Ki67>10%). Both recurrent oligometastatic disease and patients who respond to systemic treatment (ST), a radical approach with surgery or local therapy (LT) may be treatment options.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author:
Authors: Morales Herrero R, Herrero Rivera D, Santos Fernández P, Benavent M,
Keywords: ACC, chemotherapy, mitotane, local therapy,
Introduction: Results from clinical trials with telotristat ethyl (TE) are really encouraging about its role in carcinoid syndrome-associated diarrhoea, however, its efficacy in flushing has been equivocal.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author: Gertner J
Authors: Gertner J, Eastwood O, Furtado O'Mahony L, Quaglia E, McSweeney A,
Keywords: telotristat,
Introduction: The use of Twitter to disseminate medical content has increased over the last decade. Although Twitter activity by oncologists is clustered around international conferences, advocacy groups have different temporal social media patterns. Furthermore, given the non-standardized method of indexing tweets using Twitter hashtags, it can be difficult to follow the full breadth of a topic.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author:
Keywords: Neuroendocrine Tumor, Social Media, Twitter, Advocacy,
Introduction: Neuroendocrine tumors (NET) are a heterogeneous group of malignancies with varied histology, localization and behaviour.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author: Liberini V
Authors: Liberini V, De Santi B, Gallio E, Rampado O, Dionisi B,
Keywords: NET, heterogeneous, 68Ga-DOTATOC, contouring methods, LIFEx, radiomic, texture features, PET/CT,