Abstract Library

#2996 A Head-to-Head Comparison between Two Software Packages for Hybrid Dosimetry after PRRT

Introduction: The number of dosimetry studies after PRRT is increasing, yet different methodologies are used which challenge comparison or pooling of results.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Huizing D, Peters S, Versleijen M, Martens E, Verheij M,

Keywords: dosimetry, PRRT, quantification,

#1202 Role of Amplifications in the PIK3/Akt/mTOR-Pathway in Neuroendocrine Tumors of the Small Intestine

Introduction: Amplifications in the PIK3/Akt/mTOR pathway can lead to increased proliferation and reduced apoptosis, resulting in the development of various cancers. Recently, amplifications of Akt1/2, PDGFRα/β and mTOR in small intestine neuroendocrine tumors (siNET) have been shown.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author:

Authors: Hoffmeister M, Sperveslage J, Anlauf M, Petersen K, Gress T,

Keywords: NET, gene amplification, mTOR pathway,

#1167 Cowden Syndrome and Concomitant Pulmonary Neuroendocrine Tumor: A Presentation of Two Cases

Introduction: Cowden Syndrome is a multiorgan disorder with germline mutations in the tumor suppressor gene PTEN leading to dysfunctional cell growth and risk of neoplasms in e.g. breast and thyroid, but no association with NET has been described.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author: Ringholm L

Authors: Ringholm L, Langer S, I Dali C, Petersen R, Rasmussen A,

Keywords: Cowden Syndrome, pulmonary NET,

#1150 Platelet Serotonin But Not Dopamine Concentrations Are Lower in Pancreatic Neuroendocrine Tumor and Renal Cell Carcinoma Patients Compared to Healthy Individuals.

Introduction: Platelets carry VEGF-A, serotonin and dopamine. Serotonin stimulates and dopamine inhibits tumor angiogenesis. We hypothesized that platelets are activated in tumor vasculature and release angiogenic factors, resulting in lower platelet serotonin and dopamine.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author:

Authors: Peters M, Van Faassen M, Van Asselt S, Bouma G, Meijer C,

Keywords: Serotonin, dopamine, pancreatic neuroendocrine tumor, renal cell carcinoma.,

#730 Loss of Chromosome 18 in Neuroendocrine Tumors of the Midgut

Introduction: The genetic alterations in neuroendocrine tumors (NET) of the midgut, in particular of the appendix (aNET), are poorly characterized. The most frequent chromosomal aberration in ileal NET (iNET) is the loss of one chromosome 18. The relevance of this alteration is unclear.

Conference: 10th Annual ENETSConcerence (2013)

Presenting Author:

Authors: Henopp T, Brix J, Sperveslage J, Anlauf M, Petersen K,

Keywords: chr18,