Abstract Library

#853 Paraneoplastic Encephalitis in a Patient with Exceptionally Long Survival Despite a Hepatic Metastatic Neuroendocrine Rectum Neoplasm

Introduction: We report the instructive case of a woman that was diagnosed with a neuroendocrine neoplasm (NEN) of the rectum with multiple liver metastases, who subsequently developed an anti-Ri positive paraneoplastic neurological syndrom (PNS).

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author:

Authors: Krug S, Boch M, Seipelt M, Rexin P, Gress T,

Keywords: rectum, anti-Ri, TACE, PNS,

#536 Orexins Exert a Pro-Apoptotic Effect on Neuroendocrine Tumors (NETs) in an Ex Vivo Culture Model of Tissue Slices

Introduction: Ex vivo culture models of tissue slices are suitable to test the effect of antitumor agents in human tumors. The orexins are neuropeptides binding to G protein-coupled receptors (OX1-R and OX2-R), exerting a pro-apoptotic effect in human colon and pancreatic cancer cell lines.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Palazzo M, Rebours V, Voisin T, Albuquerque M, Paradis V,

Keywords: digestive NET, orexins, apoptosis, ex vivo model,