Abstract Library

#1162 Comparative Marker Assessment in Small Cell Lung Cancer with Good and Poor Prognosis

Introduction: Small cell lung cancers (SCLC) are highly aggressive and poorly differentiated neuroendocrine neoplasms which comprise ̴̴̴15 % of all lung malignancies.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author:

Authors: Schmidt L, Specht E, Reimann C, Kaemmerer D, Wirtz R,

Keywords: SCLC, SSTR, CXCR4, proliferation,

#879 The Assessment of Proliferation in BP-NEN Entities Based on the Three Proliferation Markers Ki-67, TOP2A and RacGAP1

Introduction: The extent of cell proliferation as an important component of carcinogenesis can be detected in tumor tissues by means of various factors.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author:

Authors: Specht E, Wirtz R, Kaemmerer D, Schulz S, Sänger J,

Keywords: Ki-67, TOP2A, racGAP1, pulmonary, NEN, RT-PCR, immunohistochemistry,

#877 Immunohistochemical and qRT-PCR-Based Evaluation of Somatostatin Receptor 1 to 5 Expression in 92 Patients with Bronchopulmonary Neuroendocrine Neoplasms

Introduction: Little is known about the somatostatin receptor (SSTR) status in bronchopulmonary neuroendocrine neoplasms (BP-NEN), comprising typical carcinoids (TC), atypical carcinoids (AC), small cell lung cancer (SCLC) and large cell neuroendocrine lung carcinomas (LCNEC).

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author:

Authors: Specht E, Kaemmerer D, Wirtz R, Sänger J, Schulz S,

Keywords: somatostatin, bronchopulmonary, NEN, qRT-PCR, immunohistochemistry,

#833 The Chemokine Receptor CXCR4 – Differential Expression in Bronchopulmonary Neuroendocrine Neoplasms

Introduction: The CXCR4 is a plasma membrane chemokine receptor, which is involved in organogenesis, hematopoiesis and inflammation. Additionally, an over-expression is described for many neoplastic tissues. Here, an involvement in tumor progression, metastasis, adaptation to hypoxia and in stem cell survival is postulated.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author: Reimann C

Authors: Reimann C, Kaemmerer D, Specht E, Wirtz R, Lupp A,

Keywords: neuroendocrine, tumor, SCLC, CXCR4, IHC,