#879
The Assessment of Proliferation in BP-NEN Entities Based on the Three Proliferation Markers Ki-67, TOP2A and RacGAP1
Introduction:
The extent of cell proliferation as an important component of carcinogenesis can be detected in tumor tissues by means of various factors.
Conference:
11th Annual ENETSConcerence (2014)
Presenting Author:
Authors:
Specht E,
Wirtz R,
Kaemmerer D,
Schulz S,
Sänger J,
Keywords:
Ki-67,
TOP2A,
racGAP1,
pulmonary,
NEN,
RT-PCR,
immunohistochemistry,
#877
Immunohistochemical and qRT-PCR-Based Evaluation of Somatostatin Receptor 1 to 5 Expression in 92 Patients with Bronchopulmonary Neuroendocrine Neoplasms
Introduction:
Little is known about the somatostatin receptor (SSTR) status in bronchopulmonary neuroendocrine neoplasms (BP-NEN), comprising typical carcinoids (TC), atypical carcinoids (AC), small cell lung cancer (SCLC) and large cell neuroendocrine lung carcinomas (LCNEC).
Conference:
11th Annual ENETSConcerence (2014)
Presenting Author:
Authors:
Specht E,
Kaemmerer D,
Wirtz R,
Sänger J,
Schulz S,
Keywords:
somatostatin,
bronchopulmonary,
NEN,
qRT-PCR,
immunohistochemistry,
#833
The Chemokine Receptor CXCR4 – Differential Expression in Bronchopulmonary Neuroendocrine Neoplasms
Introduction:
The CXCR4 is a plasma membrane chemokine receptor, which is involved in organogenesis, hematopoiesis and inflammation. Additionally, an over-expression is described for many neoplastic tissues. Here, an involvement in tumor progression, metastasis, adaptation to hypoxia and in stem cell survival is postulated.
Conference:
11th Annual ENETSConcerence (2014)
Presenting Author:
Reimann C
Authors:
Reimann C,
Kaemmerer D,
Specht E,
Wirtz R,
Lupp A,
Keywords:
neuroendocrine,
tumor,
SCLC,
CXCR4,
IHC,
