Abstract Library
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ENETS Abstract Search
Introduction: Prolonged biochemical remission after treatment with steroidogenesis inhibitors has been described in patients with Cushing’s syndrome due to ectopic adrenocorticotropin hormone (ACTH) production. Some studies have suggested antiproliferative and apoptotic effect of ketoconazole in human cancer cells.
Conference: 15th Annual ENETSConcerence (2018)
Presenting Author: Herrera-Martínez A
Authors: Herrera-Martínez A, Feelders R, Castaño J, Van Dungen R, Dogan-Oruc F,
Keywords: ACTH- and non-ACTH producing NETs, ketoconazole, somatostatin analogs, apoptosis, cytotoxicity,
#2216 Predicting Response to PRRT: Development and Validation of a Blood-Based Predictive Biomarker
Introduction: We have developed a blood-based tool (gene expression analysis and tumor grade) for predicting PRRT efficacy.
Conference: 15th Annual ENETSConcerence (2018)
Presenting Author: Bodei L
Authors: Bodei L, Kidd M, van der Zwan W, Singh A, Severi S,
Keywords: Biomarker, carcinoid, PRRT, prediction, therapy, efficacy, stratification,
Introduction: Specific biomarkers for predicting response and risk of recurrence after surgery for enteropancreatic neuroendocrine tumours (EP-NETs) are still lacking.
Conference: 15th Annual ENETSConcerence (2018)
Presenting Author: Partelli S
Authors: Partelli S, Kidd M, Muffatti F, Andreasi V, Giannone F,
Keywords: NETest, biomarker, Enteropancreatic Neuroendocrine Tumors, diagnosis, surgery,
Introduction: Studies have implicated EGFR, IGF and mTOR signaling pathways in the regulation of pNET growth. Interpretation of these studies is complex due to tumor subtype heterogeneity and differences in molecular analysis.
Conference: 14th Annual ENETSConcerence (2017)
Presenting Author: Speel E
Authors: Henfling M, Versleijen-Jonkers Y, Starke A, Riedl R, Sprij-Mooij D,
#1916 Circulating Neuroendocrine Transcripts and Gene Cluster Analysis Predict the Efficacy of PRRT
Introduction: Prediction of PRRT efficacy is critical. We tested a blood-based multigene NET transcript analysis (NETest) to predict efficacy in 2 PRRT-treated NET cohorts. The algorithm comprises >50 genes + clusters of growth factor signaling (GFS) and metabolism (MTB).
Conference: 14th Annual ENETSConcerence (2017)
Presenting Author: Bodei L