Abstract Library
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ENETS Abstract Search
#2199 Systematic Evaluation of the Immune Microenvironment of Neuroendocrine Tumors (NET)
Introduction: Immunotherapy is being explored in many tumour types with encouraging results, but its role in the management of NET is yet to be defined.
Conference: 15th Annual ENETSConcerence (2018)
Presenting Author: Vesely C
Authors: Vesely C, Childs A, Wong Y, Ogunbiyi O, Gander A,
Keywords: immunotherapy, neuroendocrine tumor, immune landscape, checkpoint molecules, t cells,
Introduction: The identification and characterization of CTCs as part of a minimally invasive “liquid biopsy” provides an opportunity to explore NET biology, identify therapeutic targets and investigate tumour heterogeneity.
Conference: 15th Annual ENETSConcerence (2018)
Presenting Author: Childs A
Authors: Childs A, Vesely C, Rizzo F, Ensell L, Lowe H,
Keywords: CTCs, tumor heterogeneity, CNV,
Introduction: Bone metastases have been described in up to 32% of NET patients and are associated with a worse clinical outcome. Overexpression of CXCR4 in primary tumors appears predictive of skeletal involvement.
Conference: 15th Annual ENETSConcerence (2018)
Presenting Author:
#1415 Detection of SSTR2 and 5 Expression on Circulating Tumour Cells in Neuroendocrine Tumours
Introduction: Neuroendocrine tumours (NET) overexpress somatostatin receptors (SSTR) which can be targeted for therapy with somatostatin analogues (SSA) or radionuclide treatment.
Conference: 13th Annual ENETSConcerence (2016)
Presenting Author: Childs A
Introduction: Circulating Tumor Cells (CTCs) have been detected in patients with neuroendocrine tumors (NET) using the CellSearch platform. Their presence is associated with a worse clinical outcome but less than 50% patients have detectable cells. The GILUPI Cell Detector is an EpCAM coated wire that is inserted into a vein and has been developed to increase capture of CTCs.
Conference: 11th Annual ENETSConcerence (2014)
Presenting Author:
Authors: Mandair D, Ensell L, Vesely C, Lowe H, Caplin M,
Keywords: CTCs, EpCAM, neuroendocrine,