Abstract Library

#4021 What is the carcinoid syndrome? A critical appraisal of its proposed mediators

Introduction: Carcinoid syndrome (CS) is a debilitating disease that affects approximately 20% of patients with neuroendocrine neoplasms (NEN). Due to the increasing incidence and improved overall survival of patients with NEN over recent decades, patients are increasingly suffering from chronic and refractory CS symptoms. At present, symptom control is hampered by an incomplete understanding of the pathophysiology of this syndrome.

Conference:

Presenting Author: Mulders M

Authors: Mulders M, de Herder W, Hofland J,

Keywords: carcinoid, syndrome, neuroendocrine, tumor, serotonin, tachykinin, catecholamine, histamine,

#3715 Finding the frequency of bronchial carcinoid tumors associated with neuroendocrine syndrome

Introduction: Pulmonary carcinoid tumors are part of bronchopulmonary neuroendocrine neoplasms (bpNETs) along with large and small cell pulmonary carcinoma. They are capable of producing a variety of peptides and biological active hormones such as serotonin, histamine, bombesin thus leading to several endocrine syndromes.

Conference:

Presenting Author:

Authors: Fatima A,

Keywords: bronchial carcinoid, pulmonary carcinoma, carcinoid syndrome,

#3381 Time to reclassify gastric carcinomas of diffuse type to neuroendocrine carcinomas

Introduction: The difference between adeno- and neuroendocrine carcinomas has been disputed for decades. Occurrence of neuroendocrine tumor cells in adenocarcinomas has been recognized, but the distinction between them has been made upon a certain number of tumor cells with a neuroendocrine marker. The number of positive cells depends upon the sensitivity of the method. Carcinogenesis generally results in loss and not gain of function. New gene expression of markers specific for a cell type seldom occurs.

Conference:

Presenting Author: Waldum H

Authors: Waldum H, Mjønes P,

Keywords: adenocarcinoma, neuroendocrine carcinoma, neuroendocrine tumor (NET), classification,

#2164 A Case of Carcinoid Induced Heart Disease

Introduction: Carcinoid Heart disease is a common disease with neuroendocrine malignancies that invade the liver due to the paraneoplastic effects of vasoactive substances such as 5-hydroxytryptamine, histamine and tachykinins released by malignant cells rather than any direct metastatic involvement of the heart.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Ashraff S

Authors: Ashraff S, MacGowan G, Perros P, James A,

Keywords: Carcinoid, Heart disease, heart valves,

#2010 A case of Carcinoid Crisis Despite High Dose Somatostatin Analogue Therapy Peri-operatively

Introduction: Carcinoid crisis is a life threatening endocrine emergency. Somatostatin analogues (SSA) are recommended as prophylactic administration before invasive procedures. It remains unclear whether there is an optimal dose of prophylactic somatostatin analogue therapy in the peri-operative period.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Pitfield D, Casey R, Seetho I, Shaw A, Buscombe J,

Keywords: carcinoid syndrome, carcinoid crisis, octreotide, surgery,