#3210
“Lung side & sites”, the importance of localization and prognostic implications in pulmonary neuroendocrine tumors: An Italian-Spanish multicentric study of 139 cases
Introduction:
Well-differentiated neuroendocrine lung tumors (Lung NET) are classified as typical (TC) and atypical (AC) carcinoids, based on mitotic counts and the presence of necrosis. However, a prognostic role for primary tumor localization (central vs peripheral and right vs left) has not been established yet.
Conference:
18th Annual ENETS Concerence (2021)
Presenting Author:
Authors:
La Salvia A,
Persano I,
Verrico M,
Bassi M,
Modica R,
Keywords:
lung neuroendocrine tumor,
primary tumor's side (left versus right),
tumor site (peripheral versus central),
prognostic factors,
survival,
#78
The diagnostic and prognostic value of elevated proGRP levels in well- and moderately differentiated neuroendocrine tumors
Introduction:
Chromogranin A (CgA) is the most frequently used marker in well- (grade 1) and moderately (grade 2) differentiated NETs. Although CgA is a more sensitive marker than the 5-HIAA, which was widely used until the last decade, CgA has some limitations. False-positively elevated CgA may occur in renal impairment, atrophic gastritis and during treatment of proton-pump inhibitors. Progastrin-releasing peptide (proGRP) was recently reported as a promising tumor marker for small cell lung cancer. Limited data suggests that ProGRP may be a potential tumor marker in NE tumors.
Conference:
7th Annual ENETSConcerence (2010)
Presenting Author:
Authors:
Korse C,
Bonfrer J,
van den Heuvel M,
van Velthuysen M,
Vincent A,
Keywords:
Well- and moderately differentiated neuroendocrine tumors,
proGastrin Releasing Peptide,
chromogranin A,
lung tumors,