Abstract Library

#4497 Complex management of a long-term gastrinoma survivor with multimodal treatment approaches

Introduction: The prognosis of pancreatic gastrinomas is influenced by tumour burden, extent of metastasis, and treatment response, with 5-year survival rates ranging from 20% to 40%. Treatment for well-differentiated tumours typically include locoregional therapies, long-acting somatostatin analogues, molecular targeted agents, radionuclides, and chemotherapy.

Conference:

Presenting Author: Puscasu A

Authors: Puscasu A, Miron M, Croitoru A,

Keywords: gastrinoma, neuroendocrine tumour, long survival, complex management,

#3631 Are hemicolectomies still indicated in patients with neuroendocrine tumors of the appendix 1-2cm? A retrospective Europe-wide cohort study

Introduction: Awareness of a potential global overtreatment by performing oncological resections for appendiceal neuroendocrine tumors (aNET) 1-2cm is increasing.

Conference:

Presenting Author: Nesti C

Authors: Nesti C, Bräutigam K, Zwahlen M, Perren A,

Keywords: appendix, neuroendocrine tumor, surgery, hemicolectomy, metastasis, survival,

#3575 Claudin 18 immunohistochemistry for determining site of origin of metastatic neuroendocrine tumor

Introduction: Claudin 18 isoform 2 (CLDN18.2) is selectively expressed in normal and neoplastic gastric tissue and some pancreatic neoplasia. Anti-CLDN18.2 is an investigational therapy in gastric and pancreatic adenocarcinoma and a sensitive and specific immunohistochemical marker in these cancers.

Conference:

Presenting Author: Smith B

Authors: Smith B, Rice K, Setthavongsack N, Woltjer R, Wong M,

Keywords: neuroendocrine, immunohistochemistry, claudin 18, CLDN18, gastric,

#3479 Mesenteric fibrosis in SI-NEN is characterized by strong dysregulation of CXCL9, IL6, COMP and COL6A6 genes

Introduction: Small intestine neuroendocrine neoplasms (SI-NENs) are characterized by the development of desmoplastic mesenteric fibrosis (MF) in up to 50 % of cases. This can cause intestinal obstruction and ischemia, which is a significant clinical problem.

Conference:

Presenting Author:

Authors: Graf S, Keber C, Hattesohl A, Denkert C, Di Fazio P,

Keywords: si-nen, si-net, comp, col6a6, cxcl9, il6, mesenteric fibrosis, desmoplasia, desmoplastic reaction, tumor microenvironment, tme, tumor stroma interaction, next generation sequencing, ngs, htg edgeseq, gene expression analysis, rna,

#3293 Clinicopathological features and risk analysis of lymph node metastasis in type 3 gastric neuroendocrine tumor

Introduction: Type 3 gastric neuroendocrine tumor (NET) are a rare tumor and its high-risk factors of lymph node metastasis remain unclear.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author:

Authors: Li Y, Tan H,

Keywords: type 3 gastric neuroendocrine tumor, clinicopathological features, lymph node metastases,