Abstract Library

#4004 Prevalence of depressive and anxiety symptoms and disorders in neuroendocrine neoplasms: A systematic review and meta-analysis

Introduction: Neuroendocrine neoplasms (NENs) represent a heterogeneous and rare category of tumors. Currently, the prevalence of anxiety and depression among NEN population remains unknown.

Conference:

Presenting Author: Chen X

Authors: Chen X, Lu C, Yu F, Cheng Z, Chen Y,

Keywords: neuroendocrine neoplasm, anxiety, depression, systematic review,

#3938 Brachytherapy in craniopharyngiomas: A systematic review and meta-analysis of long-term follow-up

Introduction: Brachytherapy has been indicated as an alternative option for treating cystic craniopharyngiomas (CPs). The potential benefits of brachytherapy for CPs have not yet been clarified. The purpose of this work was to conduct a meta-analysis to analyze the long-term efficacy and adverse reactions profile of brachytherapy for CPs.

Conference:

Presenting Author:

Authors: Zhang L, Guo W, Pan H,

Keywords: Brachytherapy, Craniopharyngiomas, Irradiation, Efficacy,

#3876 Comprehensive characterization of the NET methylome

Introduction: The methylome holds great promise for biomarker discovery in neuroendocrine tumors (NETs), as changes in DNA methylation allow differentiation into relevant subgroups and reveal tissue of origin. However, a comprehensive characterization of the NET methylome is lacking, hampering biological insight and meaningful biomarker selection.

Conference:

Presenting Author: Mariën L

Authors: Mariën L, Ibrahim J, Cremers T, Lybaert W, Prenen H,

Keywords: neuroendocrine tumor, DNA methylation, pathway analysis, biomarker selection,

#3864 Efficacy and safety of capecitabine and temozolomide (CAPTEM) in advanced gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN) – A systematic review and metanalysis

Introduction: Gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN) are heterogeneous tumors, with multiple therapeutic options for advanced stages. The combination of capecitabine and temozolomide (CAPTEM) is increasingly used for advanced GEP-NEN, but evidence on results is sparse.

Conference:

Presenting Author: Tacelli M

Authors: Tacelli M, Massironi S, Gallo C, Bina N, Stornello C,

Keywords: chemotherapy, pfs, progression-free survival, adverse events,

#3736 Risk of complications after biopsy in pheochromocytoma and paraganglioma

Introduction: Core needle biopsy (CNB) has been used with caution in pheochromocytoma and paraganglioma (PPGL) due to concerns about catecholamine-related complications. While it is unclear what scientific evidence supports this claim, it has limited the acquisition of biological samples for diagnostic purposes and research, especially in metastatic PPGL.

Conference:

Presenting Author: Zhang L

Authors: Zhang L, Åkerström T, Mollazadegan K, Beuschlein F, Pacak K,

Keywords: Pheochromocytoma, paraganglioma, core needle biopsy, diagnosis, risk,