Abstract Library

Welcome to the open-access search for all ENETS abstracts presented at the Annual ENETS Conferences.

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ENETS Abstract Search

#4534 Development of new 3D in vitro models for pancreatic neuroendocrine tumours (PanNETs)

Introduction: Current PanNET in vitro models struggle to accurately replicate the tumour’s biology and microenvironment, limiting understanding of the mechanisms underlying PanNET behaviour and drugs response.

Conference:

Presenting Author:

Authors: Battistella A, Pinos R, Barbaglio F, Capurso G, Schiavo Lena M,

Keywords: Preclinical models, Pan NET, microenvironment, bioprinting, tumour slices, drug testing,

#4476 Pancreatic stellate cells promote tumorigenesis and progression of pancreatic neuroendocrine tumours through SERPINE2 and KCNA5

Introduction: Pancreatic stellate cells (PSC) are stromal cells in the pancreas that play a significant role in pancreatic pathology. Nevertheless, few studies have explored the significance of PSC in pancreatic neuroendocrine tumours (panNET). Their contribution to the fibrotic responses in panNET remains poorly understood. How PSC promote tumorigenesis and differentiation in panNET after being activated to myofibroblasts or cancer-associated fibroblasts (CAF) has not been studied.

Conference:

Presenting Author: Tang Q

Authors: Liu J, Li X, Bai J, Tang Q,

Keywords: caf, stellate cell, pan NET, Oncogenes,

#2073 Epigenetic Modulation of Autophagy in Pancreatic Spheroid Cells

Introduction: Pancreatic neuroendocrine malignancy is rising up in the last decade. Despite surgical resection and palliative therapy, an effective therapy has not been developed yet.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Matrood S

Authors: Matrood S, Wissniowski T, Wiese D, Gress T, Bartsch D,

Keywords: spheroid, autophagy, pancreatic neuroendocrine tumor, AMPK-alpha, stellate cells,

#2030 Autophagy Process in Pancreatic Neuroendocrine Tumor Cells

Introduction: Pancreatic neuroendocrine malignancy is rising up in the last decade. Despite surgical resection and palliative therapy, an effective therapy has not been developed yet.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Matrood S

Authors: Matrood S, Wissniowski T, Wiese D, Buchholz M, Gress T,

Keywords: autophagy, pancreatic neuroendocrine tumor, AMPK-alpha,