Abstract Library
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ENETS Abstract Search
Introduction: Serotonin-secreting pancreatic neuroendocrine neoplasms (5-HT-secreting pNENs) are very rare. They are characterised by high urinary 5-hydroxyindole-acetic acid (5-HIAA) levels (or high serum 5-HT levels).
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author:
Authors: Milanetto A, Fassan M, Gais Zürcher A, David A, Pasquali C,
Keywords: Pancreatic neuroendocrine neoplasm, primary pancreatic carcinoid, serotonin-secreting pancreatic tumour, serotonin-producing pancreatic tumour,
Introduction: Treatment of advanced neuroendocrine tumors aims to relieve symptoms and suppress tumor growth. Primary findings from the TELEACE study suggested telotristat ethyl (TE) may reduce tumor size and impact tumor growth.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author: Metz D
Authors: Metz D, Liu E, Joish V, Huynh L, Cheng M,
Keywords: neuroendocrine tumor, carcinoid syndrome, telotristat ethyl, serotonin, tumor growth, progression-free survival,
Introduction: Somatostatin analogues (SSA) are standard for symptomatic patients with neuroendocrine tumours (NETs). However, most patients experience tachyphylaxis, and limited options exist for this refractory carcinoid syndrome (RCS). Recently, ondansetron has been associated with reduction of bowel movement in a small series.
Conference: 15th Annual ENETSConcerence (2018)
Presenting Author: Kiesewetter B
Authors: Kiesewetter B, Duan H, Haug A, Riss P, Selberherr A,
Keywords: carcinoid syndrome, ondansetron, 5-HT3 antagonist, neuroendocrine tumor, somatostatin, analogues,
Introduction: Cellular adhesion molecules play an important role in tumor progression and metastasis.
Conference: 11th Annual ENETSConcerence (2014)
Presenting Author:
Authors: Rosiek V, Foltyn W, Strzelczyk J, Zemczak A, Kos-Kudła B,
Keywords: neuroendocrine neoplasms, sVCAM-1, histological grade, clinical stage,
Introduction: Several studies have shown altered expression of Insulin-like Growth Factor-1 (IGF-1) and its receptor (IGF-1R) in different types of cancers. Connective Tissue Growth Factor (CTGF) is triggered by Serotonin (5-HT) and Hypoxia Induced Factor 1 (HIF-1) and has been associated with tumor expansion and desmoplastic reaction in carcinoid tumors.
Conference: 11th Annual ENETSConcerence (2014)
Presenting Author:
Authors: Kanakis G, Grimelius L, Kaltsas G, Tsolakis A,