Abstract Library

#3415 The PEI-Q paradox: Qualitative assessment of exocrine function in NET patients treated with SSAs

Introduction: Somatostatin-analogues (SSAs) are first-line treatment of unresectable, symptomatic neuroendocrine tumors (NETs), though can cause pancreatic exocrine insufficiency (PEI). PEI symptoms of diarrhoea, bloating, and steatorrhea overlap with those of NETs (carcinoid sequelae), and both have a negative impact on quality of life. The Pancreatic Exocrine Insufficiency Questionnaire (PEI-Q) can be used to assess PEI; however, we hypothesise that the score will be unreliable in SSA-induced PEI due to concurrent improvement of carcinoid symptoms.

Conference:

Presenting Author: Hall L

Authors: Hall L, Powell-Brett S, Thompson O, Bradley E, Smith S,

Keywords: Pancreatic Exocrine Insufficiency (PEI), Neuroendocrine Tumor (NET), Patient Reported Outcome,

#2976 Incidence of Appendiceal NEN and Adherence to Pathological Classification Rules and Treatment Guidelines: Results of the Population Based Cancer Registry in Belgium

Introduction: Classification of appendiceal neuroendocrine neoplasms (aNEN) changed significantly over the years and treatment algorithm remains a matter of debate.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Ribeiro S

Authors: Ribeiro S, De Maeyer F, De Man M, Carton S, Cuyle P,

Keywords: appendiceal NET, incidence in community, subtypes/WHO grade, management decisions,

#2968 Incidence of Rectal NEN and Adherence to Pathology Classification Rules and Treatment Guidelines: Results of the Population Based Cancer Registry in Belgium

Introduction: Classification of rectal NEN (rNEN) changed significantly over the years.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Geboes K

Authors: Geboes K, De Maeyer F, De Man M, Ribeiro S, Carton S,

Keywords: rectum, incidence, treatment management, subtypes/who grade,

#2765 Role of Biomarkers in Disease Progression of NET

Introduction: Due to the non specific features of neuroendocrine tumors and lack of diagnostic biomarkers, the diagnosis is usually delayed and almost half of patients presenting with distant metastases

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Fatima A

Authors: Fatima A, Zaidi S,

Keywords: biomarker, CgB, CART, CgA,

#408 Expression of Cocaine- and Amphetamine-Regulated Transcript is Associated with Worse Survival in Small Bowel Carcinoid Tumors

Introduction: Cocaine- and amphetamine-regulated transcript (CART) peptide acts both as a neurotransmitter and hormone. We recently demonstrated that CART is expressed in several types of neuroendocrine tumors.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Landerholm K, Shcherbina L, Falkmer S, Järhult J, Wierup N,

Keywords: neuroendocrine tumor, carcinoid, CART, survival, prognostic factors,