Abstract Library

#1490 Even Malignant Appendiceal Neuroendocrine Tumors Exhibit No Recurrent Chromosomal Alterations

Introduction: Neuroendocrine tumors (NETs) of the midgut are located in the ileum (iNET), caecum or appendix (aNET). Despite of the similar origin, NETs of the ileum and the appendix behave remarkably different. iNETs show high malignant potential, which manifests with early lymph node or liver metastases. Genetically, the loss of chromosome 18 (Ch18) in 60-74% of cases is the most frequent alteration in iNETs. aNETs are often incidental findings, rarely show metastases, and no chromosomal alterations are known.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: Sipos B

Authors: Nann D, Nieser M, Sperveslage J, Henopp T, Vokuhl C,

Keywords: NET,

#1235 The Belgian DNET Registry: A Prospective, National, Web-Based Registry of Digestive Neuro-Endocrine Tumours (NET). Status After 2 Years of Inclusion.

Introduction: NET are rare neoplasms. The Belgian Group of Digestive Oncology created a web-based registry to have an overview on incidence, diagnosis and therapies performed in Belgian pts. The DNET registry was launched in 01/2012.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author: Borbath I

Authors: Borbath I, Dresse D, Verslype C, Demolin G, Rezai Kalantari H,

Keywords: Registry, Belgium,

#359 Expression of UCH-L1 in Pancreatic Endocrine Tumors and Its Clinical Significance

Introduction: Pancreatic endocrine tumors (PETs) are rare tumors with distinct clinical syndromes. There is a lack of reliable biomarker to distinguish benign and malignant form of PETs as well as to predict its prognosis. Our previous proteomic study on insulinoma found that overexpression of UCH-L1 in tumors. The diagnostic or prognostic value of this protein has not been well addressed in PETs.

Conference:

Presenting Author:

Authors: Qiao X, Wan Y, Tang L, Lu C, Xiao Y,

Keywords: pancreatic endocrine tumors, UCH-L1, biomarker,

#23 Developing a customized database for NET in a developing country

Introduction: The establishment of a neuroendocrine registry is extremely hard in developing countries. Many patients miss follow-up after surgical procedures and many die in different hospitals with a distinct national security health system number. As in any developing country, Brazil has a large movement of people to urban areas, making the tracking of former addresses impossible for patients who were treated some years prior. Therefore, it is more feasible to evaluate a demographic distribution of neuroendocrine tumors by topography or histological subtype, but the analysis of clinical events, such as progression-free survival, disease-free survival, time to progression or overall survival, is compromised.

Conference: 7th Annual ENETSConcerence (2010)

Presenting Author: Garicochea B

Authors: Bós A, Shavinsky C, Pereira de Carvalho G, Barcellos de Almeida P, Scandura K,

Keywords: NET, software, developing country, registry,