Abstract Library

#4011 Differences in the microRNA expression of G1 and G2 pancreatic neuroendocrine tumors

Introduction: Targeted testing of microRNAs implicated in the biology of pancreatic neuroendocrine tumors (PNET) was performed via RT-QPCR to uncover differentially expressed microRNAs that could be used as diagnostic markers characteristic for tumor grade.

Conference:

Presenting Author:

Authors: Nyirő G, Szeredás B, Vékony B, Borka K, Zalatnai A,

Keywords: miRNA expression, PNET G1 and G2, RT-QPCR, hsa-miR-130b-3p, hsa-miR-194-5p, hsa-miR-96-5p, hsa-miR-106b, FFPE tissue,

#3840 Sneak peek into neuroendocrine tumors (preliminary study) – Reconsideration of histopathological approach and classification

Introduction: Tumorlets and DIPNECH are rare entities often associated with bronchial neuroendocrine tumors and little is known regarding their clinical course and management. However, they are not uncommon findings on CT or MR imaging of patients with known bronchial NENs.

Conference:

Presenting Author:

Authors: Vamvakaris I, Evangelou G, Riga D, Jensen L, Psichoyou E,

Keywords: TUMORLETS, DIPNECH, TYPICAL CARCINOID, ATYPICAL CARCINOID, LUNG NET, BRONCHIAL NET, CLASSIFICATION,

#3832 Mutational profiling of pNETs and pNECs indicates implication of chromatin epigenetic modification

Introduction: Pancreatic neuroendocrine neoplasms (pNENs) are classified as carcinomas (pNECs), and tumors (pNETs). Their handling is challenging and understanding their carcinogenesis process including genetic-epigenetic relations is crucial for their clinical management.

Conference:

Presenting Author: Angelioudaki I

Authors: Angelioudaki I, Koniaris E, Kataki A, Loukas Y, Thodi G,

Keywords: Neuroendocrine Tumor, Neuroendocrine Carcinoma, Pancreas, Next Generation Sequencing, Epigenetics,

#3462 Development and verification of a new monoclonal OTP specific antibody for pulmonary carcinoid diagnostics

Introduction: Histology-based grading of pulmonary carcinoids (PC) is problematic and subject to high interobserver variation. Orthopedia homeobox (OTP) has shown to be an excellent prognostic marker for PCs, also indicated by the WHO. However, absence of a reliable routinely applicable monoclonal OTP antibody (mAb) hampers implementation in routine diagnostics.

Conference:

Presenting Author: Speel E

Authors: Moonen L, Derks J, Lap L, Marijnissen B, van den Bosch T,

Keywords: Orthopedia Homeobox, pulmonary carcinoid, monoclonal antibody, clinical diagnostics,

#459 Differential Claudin-1 Gene Expression in Neural Crest-Derived Tumors of Common Embryological Origin

Introduction: Pheochromocytoma and paraganglioma are neural crest-derived tumors originating from chromaffin cells, with the former being intra–adrenal in location, while the latter are extra-adrenal.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Philip B, Smith R, Lam A,

Keywords: Claudin-1,