Abstract Library

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ENETS Abstract Search

#1936 The Expression of IGF Signaling Pathway Genes Is Frequently Elevated in Pancreatic Neuroendocrine Tumors, but Is Downregulated in Metastases

Introduction: Studies have implicated EGFR, IGF and mTOR signaling pathways in the regulation of pNET growth. Interpretation of these studies is complex due to tumor subtype heterogeneity and differences in molecular analysis.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: Speel E

Authors: Henfling M, Versleijen-Jonkers Y, Starke A, Riedl R, Sprij-Mooij D,

Keywords: , ,

#319 Expression of EGFR and IGF Pathway Genes in Insulinomas

Introduction: Anti-epidermal growth factor receptor (EGFR) therapy has been suggested in patients with inoperable/progressive endocrine pancreatic tumors (EPTs). However, various % EGFR-expressing EPTs are reported.

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Henfling M, Jonkers Y, Claessen S, Ramaekers F, Starke A,

Keywords: endocrine pancreatic tumors, insulinomas, EGFR, IGF2, IGF targeting therapy ,