Abstract Library
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ENETS Abstract Search
Introduction: Studies have implicated EGFR, IGF and mTOR signaling pathways in the regulation of pNET growth. Interpretation of these studies is complex due to tumor subtype heterogeneity and differences in molecular analysis.
Conference: 14th Annual ENETSConcerence (2017)
Presenting Author: Speel E
Authors: Henfling M, Versleijen-Jonkers Y, Starke A, Riedl R, Sprij-Mooij D,
Introduction: Lung carcinoids are well-differentiated neuroendocrine tumors (NETs) usually associated with a favorable prognosis. Mechanisms underlying progression are poorly understood.
Conference: 10th Annual ENETSConcerence (2013)
Presenting Author:
Authors: Swarts D, Van Neste L, Henfling M, Eijkenboom I, Van Velthuysen M,
Keywords: bronchial carcinoids, cDNA microarray, chromosomal passenger complex, immunohistochemistry, progression,
Introduction: Lung carcinoids comprise a heterogeneous group of neuroendocrine tumors. Only few parameters have been identified that correlated with poor disease outcome, including 11q22-q25 deletions. New biomarkers are required to further improve diagnosis and prediction of prognosis.
Conference: 9th Annual ENETSConcerence (2012)
Presenting Author:
Authors: Swarts D, Van Neste L, Henfling M, Van Suylen R, Volante M,
Keywords: Bronchial carcinoids, cDNA microarray, MEN-2,
#319 Expression of EGFR and IGF Pathway Genes in Insulinomas
Introduction: Anti-epidermal growth factor receptor (EGFR) therapy has been suggested in patients with inoperable/progressive endocrine pancreatic tumors (EPTs). However, various % EGFR-expressing EPTs are reported.
Conference: 8th Annual ENETSConcerence (2011)
Presenting Author:
Authors: Henfling M, Jonkers Y, Claessen S, Ramaekers F, Starke A,
Keywords: endocrine pancreatic tumors, insulinomas, EGFR, IGF2, IGF targeting therapy ,
#212 Reduced MEN1 Gene Expression in Pulmonary Carcinoids Is Associated With Metastatic Disease
Introduction: Lung carcinoids are neuroendocrine tumors that can be classified as typical (TC) or atypical (AC) carcinoids. Previously, MEN-1 mutations and associated LOH of 11q13 have been implied in tumorigenesis.
Conference: 8th Annual ENETSConcerence (2011)
Presenting Author:
Authors: Swarts D, Henfling M, Ramaekers F, Van Suylen R, Dingemans A,
Keywords: bronchial carcinoids, methylation specific PCR, multiple endocrine neoplasia type 1, hypermethylation,