Abstract Library

#319 Expression of EGFR and IGF Pathway Genes in Insulinomas

Introduction: Anti-epidermal growth factor receptor (EGFR) therapy has been suggested in patients with inoperable/progressive endocrine pancreatic tumors (EPTs). However, various % EGFR-expressing EPTs are reported.

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Henfling M, Jonkers Y, Claessen S, Ramaekers F, Starke A,

Keywords: endocrine pancreatic tumors, insulinomas, EGFR, IGF2, IGF targeting therapy ,

#212 Reduced MEN1 Gene Expression in Pulmonary Carcinoids Is Associated With Metastatic Disease

Introduction: Lung carcinoids are neuroendocrine tumors that can be classified as typical (TC) or atypical (AC) carcinoids. Previously, MEN-1 mutations and associated LOH of 11q13 have been implied in tumorigenesis.

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Swarts D, Henfling M, Ramaekers F, Van Suylen R, Dingemans A,

Keywords: bronchial carcinoids, methylation specific PCR, multiple endocrine neoplasia type 1, hypermethylation,