Abstract Library

#4031 68-Gallium DOTANOC PET/CT pitfall in adnexal tumor

Introduction: PET/CT with 68Ga-DOTA is a commonly used tool in the baseline evaluation and follow-up of NETs due to its high specificity and sensitivity, showing better performance than CT in detecting primary and metastatic disease. However, we must know more about its normal physiological distribution, its variation in pathologies, and the possibility of confusion with benign processes to optimize its interpretation.

Conference:

Presenting Author:

Authors: González Devia D, Chaar-Lugo A, Rojas-Camacho J, Londoño-Schimmer E, Buriticá-Cifuentes C,

Keywords: Neuroendocrine tumor, 68Ga-DOTANOC, PET/CT, Rectal neuroendocrine tumor, Adnexal tumor, Pitfalls,

#3922 National registry of pheochromocytomas and paragangliomas in the Colombian territory: Epidemiological insights and clinical profiles

Introduction: Limited epidemiological data exist concerning pheochromocytomas and sympathetic paragangliomas (PPGL) in Latin America, resulting in a reliance on small cohorts and case reports that may not accurately represent the true behavior of these tumors in the population.

Conference:

Presenting Author: Zea Lopera J

Authors: Zea Lopera J, Agredo Delgado V, Román González A, Donado Gómez J, Jiménez C,

Keywords: Pheochromocytoma, paraganglioma, PPGL, neuroendocrine tumor, incidentaloma, clinical presentation,

#3764 Therapeutic response of ACTH-dependent ectopic Cushing's syndrome to low doses of osilodrostat

Introduction: Cushing's disease (CD) is the main cause of ACTH-dependent Cushing's syndrome (ACTH-CS). In 5–15% of cases, ACTH/CRH production is ectopic and is caused by neuroendocrine tumors of the lung, thymus, or pancreas, medullary thyroid carcinoma, and pheochromocytoma. Diagnostic imaging can locate the primary tumor; however, between 8-22% the cause is unknown. The FDA approved Osilodrostat for the treatment of inoperable or refractory CD, its use in high doses in patients with ectopic CS has been reported.

Conference:

Presenting Author:

Authors: González Devia D, Florez-Romero A, Rojas-Camacho J, Herrera Almario G, Jimenez Hakim E,

Keywords: ACTH-dependent Cushing's syndrome, Osilodrostat, Adrenal steroidogenesis inhibitors, Ectopic ACTH Cushing´s syndrome,

#3756 The clinical utility of NETest in patients with small intestinal neuroendocrine neoplasms (SI-NENs) – A "real-life" study

Introduction: Management of patients with SI-NENs is challenging due to biological heterogeneity. Prognostication can be difficult, mostly due to a lack of reliable biomarkers.

Conference:

Presenting Author:

Authors: Gertner J, Hayes A, Furtado O'Mahony L, Glover T, Karia P,

Keywords: Neuroendocrine neoplasm, small intestine, NETest, tumor growth rate, biomarker,

#3734 Treatment outcomes in patients with localized and advanced glucagonomas – A case series

Introduction: Glucagonomas are rare functional pancreatic neuroendocrine tumors, which are often metastatic at diagnosis. Due to their low prevalence, the effectiveness of available treatment modalities remains unclear.

Conference:

Presenting Author: Armeni E

Authors: Porto J, Alexander B, Armeni E, Hesketh R, Mandair D,

Keywords: glucagonoma, treatment lines, progression-free survival, overall survival,