Abstract Library
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ENETS Abstract Search
#1227 Molecular Profiling of Small Intestinal Neuroendocrine Tumours (SINETs)
Introduction: Aberrant DNA methylation plays an role in the pathogenesis of many cancers, however little is known about its role in SINET development.
Conference: 12th Annual ENETSConcerence (2015)
Presenting Author: Thirlwell C
Authors: Karpathakis A, Feber A, Morris T, Dibra H, Pipinikas C,
Keywords: Epigenetics, methylation, GIPR, biomarker,
#936 Promoter Hypermethylation at RASSF1 is a Feature of Small Intestinal Neuroendocrine Tumors
Introduction: Promoter hypermethylation of RASSF1 has been reported in many tumor types.
Conference: 11th Annual ENETSConcerence (2014)
Presenting Author: Karpathakis A
Authors: Karpathakis A, Dibra H, Morris T, Feber A, Mandair D,
Keywords: Epigenetics, methylation, RASSF1,
Introduction: We have previously demonstrated that Circulating Tumor Cells (CTCs) can be detected in patients with neuroendocrine tumors (NET) and that their presence is prognostic. Downstream analysis of CTCs provides an opportunity to explore their potential as biomarker for targeted therapy. Here we present initial data which demonstrates that molecular profiling can be successfully performed on single CTCs from patients with NETs
Conference: 10th Annual ENETSConcerence (2013)
Presenting Author:
Authors: Mandair D, Karpathakis A, Lowe H, Griffin N, Caplin M,
Keywords: circulating tumor cells, biomarker,
Introduction: Histopathological recognition of neuroendocrine tumors (NETs) is straightforward, however, sub-classification, grading and staging is challenging with frequently evolving pathological criteria.
Conference: 10th Annual ENETSConcerence (2013)
Presenting Author:
Authors: Karpathakis A, Miki Y, Thirlwell C, Meyer T, Toumpanakis C,
Keywords: histopathology, Ki-67, staging,