Abstract Library

#4178 MEN1 syndrome across four generations

Introduction: MEN1 should be suspected in patients with an endocrinopathy of two of the three typically affected organs, or with an endocrinopathy of one of these organs and a first-degree relative affected by MEN1 syndrome. Still, a delay in diagnosis occurs in most cases.

Conference:

Presenting Author:

Authors: Ciobanu O, Martin S, Muha M, Fica S,

Keywords: MEN1 syndrome, large kindred, case series,

#3971 Clinical manifestation and aggressiveness of duodenopancreatic neuroendocrine tumors (DP-NET) in patients with MEN1 syndrome: A possible role of exon 2 mutations in menin gene

Introduction: Multiple endocrine neoplasia type 1 (MEN1) is a rare syndrome characterized by co-occurrence of primary hyperparathyroidism (PH), duodenopancreatic neuroendocrine tumors (DP-NET) and/or pituitary adenomas without an established genotype-phenotype correlation.

Conference:

Presenting Author: Benevento E

Authors: Benevento E, Liccardi A, Minotta R, Cannavale G, Di Iasi G,

Keywords: Multiple endocrine neoplasia type 1 (MEN1), exon two, genomic, primary hyperparathyroidism, duodenopancreatic neuroendocrine tumor, DP-NET, pituitary adenomas,

#3896 Diagnostic utility of menin immunohistochemistry in MEN1 syndrome patients

Introduction: A clinical diagnosis of Multiple Neoplasia type 1 (MEN1) syndrome is confirmed with genetic testing. It is expected that menin protein expression is lost in MEN1 related tumors.

Conference:

Presenting Author: Verschuur A

Authors: Verschuur A, Kok A, Morsink F, de Leng W, van den Broek M,

Keywords: MEN1, MEN1 syndrome, parathyroid, parathyroid adenoma, menin, immunohistochemistry,

#3844 Post-partum insulinoma in a MEN1 patient submitted to pancreatic electroporation

Introduction: Pancreatic neuroendocrine tumors (panNET) are a frequent manifestation of MEN1 syndrome. Insulinomas are often surgically treated.

Conference:

Presenting Author: Gil-Santos S

Authors: Gil-Santos S, Santos A, Carvalho A, Oliveira J, Souteiro P,

Keywords: insulinoma, electroporation, pancreatic neuroendocrine tumor, MEN1,

#3785 MEN1 syndrome – Data from a single referral center

Introduction: The clinical presentation in multiple endocrine neoplasia type 1 (MEN1) varies among patients, from asymptomatic to significant morbidity depending on the organs affected and the hypersecretion of hormones.

Conference:

Presenting Author:

Authors: Papadopoulou-Marketou N, Alexandraki K, Panagaki M, Tsoli M,

Keywords: MEN1 syndrome, pNET, aggressive, metastatic,