Abstract Library

#4543 Single-cell transcriptomic landscape indicates the potential role of immunotherapy in metastatic pancreatic angiosarcoma

Introduction: Pancreatic angiosarcoma is a rare and highly aggressive tumour originated from lymphatic or vascular endothelial cells, with poor prognosis and few effective treatments. However, little is known about its tumour microenvironment and the mechanisms of its progression.

Conference:

Presenting Author: Yang Y

Authors: Yang Y, Chen L, Liu M, Lin X, Peng S,

Keywords: pancreatic angiosarcoma, single-cell RNA sequencing, immunotherapy, PD-L1, CD86,

#3958 Treatment strategy for pancreatic NETs smaller than 2 cm should be based on the diagnosis of malignancy as well – New treatment strategy for small pancreatic NETs

Introduction: There are still many unclear issues regarding the treatment of non-functioning small (≤20 mm) pancreatic neuroendocrine neoplasms (pNENs).

Conference:

Presenting Author: Hijioka S

Authors: Hijioka S, Yamashige D, Esaki M, Honda G, Masui T,

Keywords: small pancreatic neuroendocrine neoplasm, tumor size, grading, treatment strategy, Japanese cohort,

#3643 Effect of resection timing as part of multidisciplinary treatment for pancreatic NEN liver metastases

Introduction: Liver metastases are treated by resection if radical resection is possible as a part of multidisciplinary treatment along with pharmacotherapy and TACE.

Conference:

Presenting Author:

Authors: Masui T, Nagai K, Anazawa T, Kasai Y, Yogo A,

Keywords: liver metastasis, multidisciplinary treatment,

#2951 Analysis of Discordance between Biopsy Grade and Surgical Pathology Grade in Resected PanNEN Patients

Introduction: In PanNEN cases, treatment strategies are decided by tumor localization, volume and grade. In unresectable or metastatic cases, tumor grade is determined by biopsy specimen obtained from EUS-FNA and diagnostic accuracy of biopsy according to WHO classification 2017 is important for decision making of treatment.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Nakano K, Masui T, Yogo A, Uchida Y, Nagai K,

Keywords: PanNEN, WHO classification 2017, EUS-FNA, Ki-67, biopsy, surgical pathology, discordance,

#2886 Risk Factors for Short Recurrence-Free Survivals after Resection of PanNET Liver Metastasis: Single Institutional Analysis

Introduction: Although the treatment of PanNEN has improved survivals with development of pharmacotherapy recently, surgery is the first choice if curative resection is expected to be achieved. However, most of the patients undergo recurrence after resection of the liver metastasis even after curative resection. Therefore, it is important to identify who gains longer RFS by resection.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Masui T, Anazawa T, Nagai K, Sato A, Nakano K,

Keywords: liver metastasis, PanNEN, resection, indication,