Abstract Library

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Participants of the ENETS Conference in 2024 can now access the abstract booklet, e-posters and videos, slide decks of talks, the poster carousel, and more via My ENETS.

ENETS Abstract Search

#3003 The Proinflammatory Molecule, VAP-1, Is Enriched in the Stroma of Midgut NETs and Plaques of Carcinoid Heart Disease Valves

Introduction: Vascular adhesion protein-1 (VAP-1) is a novel driver of tissue inflammation and fibrosis.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Shah T, Sagar V, Neil D, Liu B, Barriuso J,

Keywords: carcinoid, GEP-NET, VAP-1, ECM, tumour stroma, biomarker,

#2833 Surgical Correction of Carcinoid Heart Disease Improves Liver Function and 5-Hydroxyindoleacetic Acid Levels

Introduction: Neuroendocrine tumours of the gastrointestinal tract cause carcinoid syndrome and carcinoid heart disease. These tumours secrete serotonin, which can bind to heart valves and cause fibrosis and valve incompetence. Most cases involve the tricuspid valve +/- pulmonary valve. Medical management comprises diuretics for fluid overload and somatostatin analogues to reduce circulating serotonin. Definitive treatment is heart-valve replacement surgery which improves exercise tolerance but has high perioperative mortality. We have previously reported that valve-replacement surgery can reduce 5-hydroxyindoleacetic acid (5-HIAA) levels, reflecting a decline in hormone activity.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Shah H

Authors: Shah H, Sagar V, Venkataraman H, Steeds R, Rooney S,

Keywords: carcinoid, carcinoid syndrome, neuroendocrine tumour, carcinoid heart disease, 5hiaa,

#1655 A Case Report of Bicaval Stents and Inferior Vena Cava Valve Implantation to Control Carcinoid Symptoms in Order to Safely Allow Surgical Valve Replacement

Introduction: Surgery for severe tricuspid regurgitation (TR) is a high-risk procedure. Therefore transcatheter valve implantation into the vena cava can be performed as an attempt to reduce the complications and symptoms associated with this.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author:

Authors: Sagar V, Steeds R, Doshi S, Shetty S, Shah T,

Keywords: Carcinoid heart disease, neuroendocrine tumors,

#1654 A Single Centre Analysis of the Management of Appendiceal Neuroendocrine Neoplasms (NENs) Including Goblet Cell Carcinoids (GCC)

Introduction: Appendiceal neuroendocrine neoplasms (NENs) are usually diagnosed incidentally on histology following an appendicectomy. They include carcinoid tumours (appendiceal neuroendocrine tumours, NETs) and goblet cell carcinoids (GCC). GCC neoplasms are able to transform to an adenocarcinoma phenotype.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author:

Authors: Sagar V, Coldham C, Shetty S, Elshafie M, Taniere P,

Keywords: Appendiceal neoplasm, neuroendocrine tumors,