Abstract Library

#1579 Establishment and Characterization of a Continuous Cell Line from a Human Familial Medullary Thyroid Carcinoma

Introduction: introduction missing

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author:

Authors: Pfragner R, Schwach G, Ghaffari Tabrizi-Wizsy N, Hoeger H, Tam-Amersdorfer C,

Keywords: Familial MTC, continuous cell line, characterisation, authentication, xenografts,

#1528 Medullary Thyroid Carcinoma Cell Lines – An Update

Introduction: Medullary Thyroid Carcinoma (MTC) originates from calcitonin-producing neuroendocrine C-cells of the thyroid gland. Mutations in the RET-proto-oncogene are associated with both sporadic and familial MTC. As MTC are poorly responsive to chemo- and radiation- therapy, surgery is the only curative treatment at the moment. The cytogenetics of MTC have been sparsely investigated because the cells are very difficult to cultivate. In the last three decades our research group has established 10 continues cell lines derived from primary tumor and lymph node metastasis of patients with either sporadic or hereditary MTC.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: Schwach G

Authors: Schwach G, Ghaffari-Tabrizi Wizsy N, Tam-Amersdorfer C, Meier-Allard N, Siddiqui Z,

Keywords: MTC continuous cell line, characterisation, xenografts,