Abstract Library

#654 Identification of Signaling Pathways Involved in Lung Carcinoid Progression Using Gene Expression Profiling

Introduction: Lung carcinoids are well-differentiated neuroendocrine tumors (NETs) usually associated with a favorable prognosis. Mechanisms underlying progression are poorly understood.

Conference: 10th Annual ENETSConcerence (2013)

Presenting Author:

Authors: Swarts D, Van Neste L, Henfling M, Eijkenboom I, Van Velthuysen M,

Keywords: bronchial carcinoids, cDNA microarray, chromosomal passenger complex, immunohistochemistry, progression,

#462 Genome-Wide Expression Profiling Reveals Downregulation of OTP and CD44 and Upregulation of RET as Indicators of Poor Prognosis in Lung Carcinoids

Introduction: Lung carcinoids comprise a heterogeneous group of neuroendocrine tumors. Only few parameters have been identified that correlated with poor disease outcome, including 11q22-q25 deletions. New biomarkers are required to further improve diagnosis and prediction of prognosis.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Swarts D, Van Neste L, Henfling M, Van Suylen R, Volante M,

Keywords: Bronchial carcinoids, cDNA microarray, MEN-2,

#360 High Resolution (Epi)genomic Analysis Comparing Pulmonary Carcinoids with a Favorable and a Poor Disease Outcome

Introduction: Lung carcinoids are a heterogenous group of neuroendocrine tumors. MEN1 mutations and 11q22-q25 deletions have been implied in their tumorigenesis. Very few genome wide and methylation studies have been conducted to further elucidate molecular mechanisms underlying tumorigenesis.

Conference:

Presenting Author:

Authors: Swarts D, Van Neste L, De Hoon J, Van Velthuysen M, Burgers J,

Keywords: Bronchial carcinoids, MIRA, Expression profiling, arrayCGH,