Abstract Library

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#1010 Soluble VCAM-1 and Its Relation to Clinical Staging and Histological Grading in Neuroendocrine Neoplasms (NENs)

Introduction: Cellular adhesion molecules play an important role in tumor progression and metastasis.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author:

Authors: Rosiek V, Foltyn W, Strzelczyk J, Zemczak A, Kos-Kudła B,

Keywords: neuroendocrine neoplasms, sVCAM-1, histological grade, clinical stage,

#801 Normal Gastrointestinal Neuroendocrine Cells Lack E-cadherin

Introduction: E-cadherin plays a crucial role in the adhesion between epithelial cells and thus epithelial integrity. Moreover, germ line mutations in the E-cadherin gene (CDH1) causing loss of E-cadherin function (adhesion) leads to hereditary gastric cancer of the diffuse type, according to Laurén. Even sporadic gastric carcinomas of the diffuse type often lose E-cadherin expression due to mutations. Lack of E-cadherin has been recorded at an early phase in such carcinomas.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author: Hauso �

Authors: Hauso �, Nordbø H, Ringnes E, Sørdal �, Nordrum I,

Keywords: E-cadherin, neuroendocrine cell, gastric cancer, adhesion molecules, neuroendocrine tumors, carcinoid,