Abstract Library

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#3168 Endocrine neoplasias and non-endocrine neoplasias associated with primary aldosteronism

Introduction: Primary aldosteronism (PA) is the main cause of secondary arterial hypertension (AH) of endocrine origin (1). Clinical presentation may include resistance to treatment for AH, hypokalemia, with the autonomous secretion of aldosterone. Somatic mutations and epigenetic factors are the most frequent etiologies (2). Adrenal tumors may be a characteristic of MEN1 syndrome (3). Some case reports have associated endocrine neoplasms with PA; however, the real prevalence of this association is unknown (3).

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Huertas Gnecco B

Authors: Huertas Gnecco B, González Devia D, Jaramillo Chacón H, López Panqueva R, Cañón Solano D,

Keywords: primary hyperaldosteronism, primary aldosteronism, neuroendocrine tumor, endocrine tumor, neoplasia,

#125 Ectopic hormone secreting phaeochromocytoma: A francophone observational study

Introduction: Ectopic hormone-secreting phaeochromocytomas are rare and only small reports of 1-2 cases exist in the literature. In the past, this condition has been linked with increased malignancy, familial syndromes and ACTH secretion.

Conference: 7th Annual ENETSConcerence (2010)

Presenting Author: Kirkby-Bott J

Authors: Kirkby-Bott J, Brunaud L, Mathonet M, Hamoir E, Kraimps J,

Keywords: phaeochromocytoma, ectopic hormone secretion, ACTH, calcitonin, VIP, Il-6, renin, aldosterone, cortisol, testosterone,

#64 Sustained response to anti IGFR-1R monoclonal antibody combined with docetaxel in a patient with metastatic adrenocortical carcinoma

Introduction: Adrenocortical carcinoma (ACC) is a rare neoplasm with poor prognosis. Treatment results in advanced disease are disappointing and median survival is less than 12 months. There is no standard chemotherapy, even though mitotane and cisplatin-based regimens are frequently used with limited efficacy. In vitro data suggest that overexpressed insulin growth factor-2 (IGF-2) acting via the IGF-1 receptor (IGF-1R) is relevant for ACC and that the IGF-1R and 2R pathway is a promising target.

Conference: 7th Annual ENETSConcerence (2010)

Presenting Author:

Authors: De Dosso S, Saletti P, Gallerani E, Terrot T, Sessa C,

Keywords: adrenocortical carcinoma, anti IGFR-1R monoclonal antibody,