Abstract Library

#4649 Claudin 18.2 overexpression in gastric neuroendocrine tumours

Introduction: Claudin 18.2, is a tissue biomarker physiologically expressed in both healthy gastric mucosa and gastric adenocarcinoma which represents a novel therapeutic target advanced gastric cancer. Various other cancers showed some overexpression of claudin 18.2 opening potential opportunities to agnostic targeted therapy. However, data about claudin 18.2 expression in NENs are poor with only an Eastern study showing higher rate of claudin 18.2 positivity in GEP-NENs, mainly from gastric primary site (27.8%).

Conference:

Presenting Author: Gervaso L

Authors: Gervaso L, Lobrano R, Pisa E, Benini L, Spada F,

Keywords: claudin, gastric NET, biomarker, Neuroendocrine tumour,

#4456 Characteristics and clinical outcomes after endoscopic or surgical resection of localised sporadic type III gastric NETs: A national study from the French Group of Endocrine Tumors and ENDOCAN-RENATEN network

Introduction: Type III gastric neuroendocrine tumours (gNETs) are rare indolent tumours with increasing incidence. Endoscopic resection has recently been described to be a safe strategy to remove small, localised type III gNETs.

Conference:

Presenting Author: Perrier M

Authors: Perrier M, Lefort R, Do Cao C, Hautefeuille V, Wallenhorst T,

Keywords: neuroendocrine neoplasm, stomach, endoscopy, surgery, carcinoid,

#4435 Clinicopathological characteristics and prognosis of 12191 patients with pancreatic neuroendocrine neoplasms

Introduction: Pancreatic neuroendocrine neoplasms (P-NENs) are a group of tumours originating from pancreatic neuroendocrine cells. Although these tumours are relatively rare, studies on them have gradually increased in recent years.

Conference:

Presenting Author:

Authors: Han D, Du H,

Keywords: Pancreatic neuroendocrine neoplasm, Multivariate analysis, Surgery,

#4404 A comparative study on the progression of neuroendocrine carcinomas and mixed neuroendocrine-non-neuroendocrine neoplasms

Introduction: The prognostic differences between neuroendocrine carcinoma (NEC) and mixed neuroendocrine-non-neuroendocrine neoplasm (MiNEN) remain unclear.

Conference:

Presenting Author:

Authors: Duan X, Yin F,

Keywords: mixed neuroendocrine–non-neuroendocrine neoplasm (MiNEN), neuroendocrine carcinoma (NEC), disease progression, treatment protocol, signalling pathway,

#4348 Real-world clinicopathological features and outcome of elderly patients with thymic neuroendocrine neoplasms: A retrospective single-institution analysis

Introduction: Thymic neuroendocrine neoplasms (TNENs）are rare and heterogeneous diseases. With the aging of society, there has been an increase in the proportion of elderly patients with TNENs，however, research on these patients is limited.

Conference:

Presenting Author:

Authors: Jia X, Sun Z, Xu J, Huang D, Chen F,

Keywords: thymic neuroendocrine tumour, aged 65 years or above, clinicopathological characteristics, survival analysis, real-world,