Abstract Library

#4614 Rare diagnosis of intrapancreatic accessory spleen mimicking PanNET

Introduction: A 44-year-old woman with hypertension and an autoimmune thyroid disease. With a positive family history of pancreatic and oesophageal cancer. Referred to our clinic for an incidental finding of a tumour in the tail of the pancreas on abdominal ultrasound by a surgeon.

Conference:

Presenting Author: Uhrík P

Authors: Uhrík P, Nosakova L, Vojtko M, Bánovčin P,

Keywords: fine needle biopsy, accessory spleen, Neuroendocrine tumour,

#4523 Preoperative evaluation of tumour border using radiomics and its surgical guidance in pancreatic neuroendocrine tumours

Introduction: Pancreatic neuroendocrine tumours are a heterogeneous group of tumours originating from peptidergic neurons and neuroendocrine cells with variable survival outcomes. Surgical resection is the mainstay of treatment. However, there is an ambiguous insight into the real need to execute the standard surgery in small pancreatic neuroendocrine tumours. The tumour border is a powerful determinant of survival prognosis in many tumours and is often used as a safety guarantee for parenchyma-sparing resections. However, there are no studies evaluating tumour border with or without preoperative imaging in pNETs.

Conference:

Presenting Author: Wang Y

Authors: Wang Y, Gu W, Tang W, Huang D, Zhang W,

Keywords: pancreatic neuroendocrine tumour, border, computed tomography, enucleation, radiomics,

#4519 ANXA1-labelled cancer-associated fibroblasts induces tumour invasion and immunosuppressive microenvironment

Introduction: The growth pattern of a tumour is a marker for distinguishing inert from invasive tumours. In general, tumours such as the encapsulated follicular variant of papillary thyroid carcinoma show expansive growth. In contrast, invasive tumours, such as colorectal cancer and squamous cell carcinoma of the tongue, show invasive growth with infiltration into surrounding structures and have a poorer prognosis. Pancreatic neuroendocrine neoplasm (PNEN) is the heterogeneous tumour originating from peptidergic neurons and neuroendocrine cells. PNEN with a high proportion of tumour mesenchyme, especially those presenting an infiltrating stroma, have a poor prognosis. In the infiltrating mesenchyme, cancer-associated fibroblasts (CAF) play an important role. However, little research has been done on the mechanisms of how infiltrating CAF affects tumour malignancy and immune microenvironment.

Conference:

Presenting Author: Wang Y

Authors: Wang Y, Xu J, Chen J, Xu X, Ji S,

Keywords: pancreatic neuroendocrine neoplasm, tumour-associated fibroblasts, immunosuppressive microenvironment,

#4394 Application of somatostatin receptor PET/CT in assisting preoperative lymph node evaluation and surgical decision-making for duodenal and pancreatic neuroendocrine neoplasms

Introduction: Preoperative precise staging of lymph nodes is crucial for determining surgical approach and extent for duodenal and pancreatic neuroendocrine neoplasms (DP-NENs), especially for small (≤2cm) DP-NENs.

Conference:

Presenting Author:

Authors: Xianze W, Bohui Y, Wenjia Z, Wensheng L, Meixi L,

Keywords: 68Ga-SSTR PET/CT, neuroendocrine neoplasm, lymph node metastasis, surgical decision-making,

#4379 Fully automated segmentation and lymph node metastasis prediction of non-functional pancreatic neuroendocrine tumours using deep learning

Introduction: Lymph node status is an important factor for the patients with NF-PanNETs with respect to surgical methods, prognosis, and recurrence. Our model serves as a non-invasive tool that supports clinical decision-making for precision surgical treatment in patients with NF-PanNETs.

Conference:

Presenting Author: Tang W

Authors: Tang W, Chen J,

Keywords: Non-functional pancreatic neuroendocrine tumour, deep learning, fully automated segmentation, imaging Informatics,