Abstract Library

#2872 Characteristics of the Immunophenotype and the Status of Receptors for Somatostatin Type 2 and 5 of Typical and Atypical Carcinoids of the Lung

Introduction: Carcinoids of the lung are a wide range of tumors with various malignancy.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Gurevich L, Voronkova I, Ashevskay V, Bondarenco E, Fedorov D,

Keywords: lung, carcinoid, immunophenotype,

#2810 Development of a Personalized Human Immunocompetent Ex-Vivo Model of Neuroendocrine Liver Metastasis Using Precision Cut Tissue Slice Technology

Introduction: Liver metastasis (LM) are very frequent (65-95%) and represent a crucial prognostic factor in patients with gastroenteropancreatic neuroendocrine neoplasms (GEP NENs). The paucity of relevant experimental models has limited the understanding of the pathophysiology of NENs and the development of efficient therapeutic strategies

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Doornebal E

Authors: Doornebal E, Harris N, Miquel R, Zen Y, Pizanias M,

Keywords: Liver, neuroendocrine liver metastasis, ex-vivo model, personalized medicine, immunocompetent, organotypic tissue slices,

#2743 Mimics of Neuroendocrine Neoplasms Identified in a Single Consultation Center between 2009 and 2019

Introduction: Immunohistochemical expression of synaptophysin (SYN), chromogranin (CgA) and cytokeratin are essential for diagnosis of NENs. Non-NENs, however, may occasionally also express NE-markers and cytokeratin and cause diagnostic difficulties.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Kasajim A

Authors: Kasajima A, Konukiewitz B, Schlitter A, Weichert W, Klöppel G,

Keywords: pitfalls, pathology diagnosis,

#1689 The Prognostic Value of the Expression of Cytokeratin 7 and 19 in Lungs and Pancreas Neuroendocrine Tumors

Introduction: The expression of cytokeratins (CK) 7,19 rarely occurs in the low grade neuroendocrine tumors (NET) of lung and pancreas. It is known that part of the low grade typical (TC) and atypical (ATС) carcinoids of lung and pancreas (pNET-G1,G2) can progress quickly and to metastasize. It is important to distinguish NET with a less differentiated cells immunophentype.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author:

Authors: Gurevich L, Korsakova N, Voronkova I, Kazanceva I, Ashevskaya V,

Keywords: neuroendocrine tumors, cytokeratin 7, 19 expression, lung, pancreas, prognostic factors,

#1402 Merkel Cell Carcinoma of Lymph Node Without Skin Primary Can - and Should - Be Distinguished from Others Metastatic Neuroendocrine Carcinoma

Introduction: Merkel cell carcinoma of lymph node without primary tumour (MCCNWP) is a rare tumour which can be misinterpreted as lymph node metastasis (LNM) from a high-grade neuroendocrine carcinoma (NEC) on histological examination. However, this distinction is crucial for therapeutic management.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: KERVARREC T

Authors: Kervarrec T, Samimi M, Beby-Defaux A, Touze A, Guyetant S,

Keywords: Merkel cell carcinoma, lymph node, MCPyV,