Abstract Library
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ENETS Abstract Search
#3028 Pancreatic Neuroendocrine Neoplasms: Dissecting the Molecular Heterogeneity
Introduction: Pancreatic neuroendocrine neoplasms (PNENs) are a group of rare but biologically and clinically heterogeneous neoplasms with variable patient outcomes. Little is known about the molecular differences between PNENs and the biologic significance of such divergence.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author:
Authors: Yang K, Kalloger S, Aird J, Lee M, Colborne S,
Keywords: Pancreatic neuroendocrine neoplasms, Exome, Transcriptome, Proteome,
Introduction: Lanreotide autogel (LAN) 120 mg every (q)28 days (standard regimen) improves progression-free survival vs placebo in patients with advanced, somatostatin receptor-positive (SSTR+) gastroenteropancreatic neuroendocrine tumours (NETs).
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author:
Authors: Ruszniewski P, Ćwikła J, Lombard-Bohas C, Borbath I, Shah T,
Keywords: Neuroendocrine tumours, lanreotide,
#2977 Predicting Survival in Patients with a Neuroendocrine Tumor of the Small Intestine (SI-NET)
Introduction: SI-NET comprise the largest group of neuroendocrine tumors. Because of their heterogeneity, predicting survival has proven challenging. A nomogram (NG) to assess SI-NET disease specific survival (DSS) has been developed in 2010 by Modlin, et al. based on analysis of retrospective data from the Surveillance, Epidemiology and End Results (SEER) database.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author:
Authors: Levy S, van Veenendaal L, Korse C, Verbeek W, Vriens M,
Introduction: Neuroendocrine tumors (NET) are a heterogeneous group of malignancies with varied histology, localization and behaviour.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author: Liberini V
Authors: Liberini V, De Santi B, Gallio E, Rampado O, Dionisi B,
Keywords: NET, heterogeneous, 68Ga-DOTATOC, contouring methods, LIFEx, radiomic, texture features, PET/CT,
Introduction: Grade 2 GEP-NETs have inherent tumor heterogeneity seen with positive expression of somatostatin (SSTR) and glucose (GLUT) receptors. Prior surgical resection and imaging parameters on Ga-68 DOTANOC PET/C are well-established variable impacting prognosis in well-differentiated grade 1 NETs. Since the degree of differentiation is variable in Grade 2 NETs, these parameters have not been studied.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author: Puranik A
Authors: Puranik A, Agrawal A, Rangarajan V, Shrikhande S, Dev I,
Keywords: Grade 2, GEP-NET, DOTANOC, surgical resection,