Abstract Library

#4635 Comparison of 18F-DOPA PET/CT and 68Ga-DOTATOC PET/CT and their impact on response to PRRT in midgut neuroendocrine tumours

Introduction: 18F-DOPA PET/CT is a powerful diagnostic test for assessing tumour burden in midgut neuroendocrine tumours (NETs). 68Ga-DOTATOC PET/CT is required for patient selection for PRRT.

Conference:

Presenting Author: Longo M

Authors: Longo M, Coccarelli A, Henry T, Kamoun T, Morbelli S,

Keywords: F-DOPA, Ga-DOTATOC, PRRT, midgut,

#4528 Serum visfatin concentration in metastatic pancreatic and midgut NETs: An exploratory study

Introduction: Neuroendocrine tumours (NETs) are commonly diagnosed at advanced stages due to their diverse and often asymptomatic clinical presentation. Visfatin, an adipocytokine involved in regulating cellular energy homeostasis, inflammation, and tumorigenesis, has been investigated as a potential biomarker in several neoplasms. However, its role in NETs remains unexplored.

Conference:

Presenting Author:

Authors: Komarnicki P, Maciejewski A, Musiałkiewicz J, Mastorakos G, Gut P,

Keywords: visfatin, biomarker, nicotinamide phosphoribosyltransferase, NAMPT, PBEF, eNAMPT,

#3962 Familial midgut neuroendocrine tumors (FM-NETs): Results of the nationwide TCF cohort from the GTE-RENATEN network

Introduction: The clinical specificities of familial midgut neuroendocrine tumors (FM-NET) have been poorly described.

Conference:

Presenting Author: de Mestier L

Authors: Hunaut T, Hercent A, Walter T, Buecher B, Lepage C,

Keywords: familial, midgut, neuroendocrine, tumors, carcinoid,

#3774 The role of the gut microbiome in patients with midgut neuroendocrine tumors

Introduction: When compared to other cancers, the prevalence of midgut neuroendocrine tumors (NETs) has disproportionally increased over the past decades. To date, very little progress has been made in the discovery of (epi)genetic drivers and treatment options of these tumors. Recent microbiome research has provided novel treatment targets among various cancer types. However, its role in midgut NETs and the Carcinoid Syndrome (CS), a frequently present syndrome of hormonal hypersecretion, has not been studied.

Conference:

Presenting Author:

Authors: Mulders M, Audhoe A, Kraaij R, van Koetsveld P, Feelders R,

Keywords: gut, microbiome, neuroendocrine, tumor, carcinoid, syndrome, diagnosis,

#3642 GP-patient interactions and coding of neuroendocrine tumors (NETs) in primary care records

Introduction: Diagnostic delays in NETs are common with improved diagnosis times recently shown in Wales. Although studies have explored GP visits, these are based on patient surveys with recall bias and no exploration of GP coded data.

Conference:

Presenting Author: Olive S

Authors: Olive S, Gould H, Navaratnam J, Khan M,

Keywords: diagnosis, GP, primary care, coding,