Abstract Library

#3034 Somatostatin Analogs for Pancreatic Neuroendocrine Tumors: Is There Any Benefit When Ki-67 Is ≥ 10%?

Introduction: The antiproliferative effect of first-line long acting somatostatin analogs (SSA) in advanced gastro-entero-pancreatic neuroendocrine tumors (GEP-NETs) was shown in the PROMID and the CLARINET trials. Efficacy data in pancreatic NETs (PanNETs) with Ki-67 ≥ 10% are limited.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Merola E

Authors: Merola E, Alonso Gordoa T, Zhang P, Al-Toubah T, Pelle E,

Keywords: Pancreatic NET, Somatostatin Analogs, Grade 2 and 3, Safety, Efficacy,

#2254 Development of a Patient-Centred Service for Neuroendocrine Tumors (NETs) in Wales: Population Based National Commissioning

Introduction: Requiring many specialities and services, NETs have complex pathways presenting a challenge to plan services in existing NHS structures

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Khan M, Reynolds M, Lewis J, Bell C, Rees A,

Keywords: Service, commissioning, Mdt,

#2229 The NETwork! Registry Suggests Increasing Incidence in a National Study of Neuroendocrine Cancer in New Zealand (NZ)

Introduction: NETwork! is a clinical and translational research program, including a retrospective epidemiological study of NETs in NZ.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Parker K

Authors: Parker K, Coats E, Woodhouse B, Knowlton N, Print C,

Keywords: neuroendocrine, incidence, epidemiology, registry,

#2226 Approaching NETs from Many Angles: A Medical Research Paradigm to Challenge New Zealand’s Research Traditions

Introduction: NETwork! is a multidisciplinary clinical and translational research program investigating NETs from several perspectives.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Parker K

Authors: Parker K, Blenkiron C, Print C, Findlay M, Lawrence B,

Keywords: neuroendocrine, translational, multidisciplinary,

#2139 Genome-Wide DNA Methylation Profiling of Pancreatic Neuroendocrine Tumors

Introduction: Frequent inactivation of epigenetic regulators ATRX and DAXX in pancreatic neuroendocrine tumors (PNETs) suggests an important role for epigenetic alterations in tumorigenesis. Few studies have been published regarding differential methylation patterns in PNETs and a thorough analysis of these alterations is currently lacking.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Boons G, Beyens M, Schepers A, Vandamme T, Roeyen G,

Keywords: pancreatic neuroendocrine tumor, DNA methylation,