Abstract Library

#4061 Dissecting the single-cell transcriptome network underlying thymic neuroendocrine tumor and thymus non-malignant tissues

Introduction: Thymic neuroendocrine tumor (TNET) is the rarest subtype among thymic epithelial tumors and NET. Limited understanding of tumor microenvironment (TME) of TNET contributes to the lack of treatment options for this rare tumor type.

Conference:

Presenting Author: Liu M

Authors: Liu M, Lin X, Chen L, Su C, Wen W,

Keywords: thymic neuroendocrine tumor, single-cell RNA sequencing, tumor microenvironment, tumor-associated fibroblasts,

#4043 Treatments, clinicopathological characteristics and prognosis in thymic neuroendocrine tumors (TNETs): With especial reference to Temozolomide (TMZ)-based chemotherapy

Introduction: Thymic neuroendocrine tumors (TNETs) are rare but aggressive malignant neoplasms that exhibit significant heterogeneity. However, there is a paucity of comprehensive clinical studies conducted to investigate the prognosis of TNETs.

Conference:

Presenting Author: Cheng Z

Authors: Cheng Z, Yu F, Cui L, Chen X, Zheng J,

Keywords: thymic neuroendocrine tumor, treatment, prognosis, temozolomide,

#3978 SDHx germline mutation in thymic neuroendocrine tumors

Introduction: Mutation in succinate dehydrogenase complex genes (SDHA, SDHB, SDHC, SDHD) could be found in 10% of hereditary paraganglioma-pheochromocytomas and gastrointestinal stromal tumors. Nearly 25% of thymic neuroendocrine tumors (TNETs) are asscociated with MEN1. TNETs asscociated with SDHx germline mutation have not been reported.

Conference:

Presenting Author: Liang Y

Authors: Liang Y, Chen J,

Keywords: SDHx，thymic neuroendocrine tumor,

#3646 Thymic neuroendocrine neoplasms – Data from the Czech Neuroendocrine Tumor Registry 2008 – 2022

Introduction: Thymic neuroendocrine neoplasms are very rare, their incidence is only 3% of all NENs a 5% of thymic tumors. On ENETS 2022 Sarah Fodil—Cherif et alt. presented data of 74 patients with thymic NETs from retrospective French study (1988-2020) and their analysis.

Conference:

Presenting Author:

Authors: Sedlackova E, Barkmanova J, Linke Z, Karpianusova T,

Keywords: thymic neoplasms, neuroendocrine tumor,

#3454 Thymic neuroendocrine tumors: Case series from a Colombian hospital reference

Introduction: Thymic neuroendocrine tumors (tNET) are extremely rare, with a wide range of clinical manifestations, which can lead to underdiagnosis. Specific therapies have not been evaluated to improve survival.

Conference:

Presenting Author:

Authors: González Devia D, Fernández Mantilla D, Pino Villareal L, Segovia Gómez J, Urrego Meléndez O,

Keywords: Thymic Neuroendocrine Carcinoma, Thymic Neuroendocrine Tumor, Neuroendocrine Carcinoma, Cushing's Syndrome, Thymus,