Abstract Library

#2205 Analysis of MET and RET Expression in Patients with Pancreatic Neuroendocrine Tumors Receiving Everolimus

Introduction: Target therapy has improved the outcome of neuroendocrine tumors (NETs), but little is known about the strategies to overcome the acquired resistance. MET is considered one of the putative mechanisms of resistance. RET is also rearranged in some other endocrine tumors (like thyroid).

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Cella C, Barberis M, Spad F, Pisa E, Laffi A,

Keywords: Everolimus, MET, RET,

#1892 Feasibility and Implication of Routine NGS Analysis in Neuroendocrine Carcinomas

Introduction: Neuroendocrine carcinomas (NECs) may arise from any organ system, exhibit various degree of differentiation and have Ki67 indices ranging from 21-100%. After first-line platin based chemotherapy, no standard treatment exists.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author:

Authors: Knigge U, Federspiel B, Andreassen M, Kjær A, Langer S,

Keywords: neuroendocrine, neuroendocrine neoplasms, neuroendocrine carcinoma, ngs, genes, mutation, ki67, tp53, kras, braf, pik3a, pten,

#1840 Genetic Features and Immunoprofile of Sporadic Well-Differentiated Neuroendocrine Tumors of Gastric

Introduction: Well-differentiated Type III gastric neuroendocrine tumors (gNET III) are histologically distinct subset that have a unique pathogenesis and clinical course.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: Ji Y

Authors: Xie Y, Xu Y, Zeng H, Wang H, Hou Y,

Keywords: genetic, wdnet.,

#775 Whole Exome Sequence Of BON-1 And QGP-1, Two Human Pancreatic Neuroendocrine Tumor Cell Lines, Reveals Homozygous Loss Of Function Mutations In TP53, HRNR and CYFIP2.

Introduction: The human BON-1 and QGP-1 cell lines are two models often used in pancreatic neuroendocrine tumor (PNET) research. Data on protein-changing mutations in these cell lines is lacking.

Conference: 10th Annual ENETSConcerence (2013)

Presenting Author: Vandamme T

Authors: Vandamme T, Op de Beeck K, Vangestel C, Pauwels P, Van Camp G,

Keywords: ,