Abstract Library

#4542 Results of active observation of pancreatic non-functioning neuroendocrine tumours – Medical registry data

Introduction: Algorithm for stage T1 pancreatic neuroendocrine tumours (PNETs) treatment requires clarification.

Conference:

Presenting Author:

Authors: Salimgereeva D, Feidorov I, Konyakhina A, Petrova A,

Keywords: Neuroendocrine tumour, PNET, pancreatic NET, management, active observation, follow-up, registry, CHEK2, oestrogen,

#4532 Gender differences in patients with medullary thyroid cancer (MTC): A single-centre experience

Introduction: Medullary thyroid cancer (MTC) accounts for 3-5% of thyroid tumours. It can be sporadic or associated with genetic syndrome. The role of gender in the MTC isn’t clarified.

Conference:

Presenting Author:

Authors: Cannavale G, Minotta R, Liccardi A, Benevento E, Di Iasi G,

Keywords: MTC, gender difference, gender medicine,

#4524 SIRT7 drives the radioresistance of pancreatic neuroendocrine tumours via the DNMT1-MEN1 axis

Introduction: Pancreatic neuroendocrine tumours (PanNETs) are a rare and highly heterogeneous type of tumour in the pancreas. After failure of standard treatment, patients have poor prognoses. Radiotherapy may be a potential therapeutic modality for such patients. However, PanNETs usually exhibit a radiation “cold” tumour through unclarified mechanisms.

Conference:

Presenting Author: Jianyun J

Authors: Jiang J, Xu J, Liang Y, Chen L, Ji S,

Keywords: pancreatic neuroendocrine tumour, radio resistance, SIRT7, MEN1,

#4406 Fluorescence labelled plasma derived small extracellular vesicle as biomarkers in metastatic pancreatic neuroendocrine tumour patients

Introduction: Pancreatic neuroendocrine tumours (PanNET) are rare with increased annual incidence rate 1/lac. There are no specific biomarkers, diagnostic and prognostic tests available for PanNET. The small extracellular vesicles (sEV) play a key role in tumour growth and metastasis and can be a potential biomarker for metastasis of PanNET.

Conference:

Presenting Author:

Authors: As S, Gorai P, Naik M, Kumar R, Kumar S,

Keywords: Metastasis, Pancreatic neuroendocrine tumour, Small extracellular vesicles, Fluorescence, Nanoparticle tracking analysis,

#4047 The role of adipocytes in neuroendocrine neoplasms: Molecular and metabolic adaptations

Introduction: It is recognized that the adipose tissue plays a major role in cancer. Recent evidence suggests the existence of altered metabolic pathways in neuroendocrine neoplasms (NENs), influencing tumor development and evolution, and thereby clinical outcomes.

Conference:

Presenting Author: Calabrese C

Authors: Calabrese C, Dellavalle S, Miserocchi G, Gabellone S, Spadazzi C,

Keywords: neuroendocrine neoplasm, adipocytes, metabolism, RNA-seq, 3D co-cultures,