Abstract Library

#4364 Single agent axitinib in the management of patients with progressive pheochromocytoma and paraganglioma

Introduction: Radiolabelled therapy with meta-iodobenzguanine (MIBG) and chemotherapy with a combination of cyclophosphamide, vincristine, and dacarbazine can help manage patients with metastatic pheochromocytoma and paraganglioma (mPPGL). The phase II FIRSTMAPPP study supports the use of the tyrosine kinase inhibitor sunitinib in these malignancies, with median progression-free survival values of 8.9 versus 3.6 months and overall response rates of 31% versus 8% for sunitinib versus placebo. The median duration of sunitinib therapy was 11 months. Concurrent with this study, we launched a single-arm trial to examine the activity of a similar tyrosine kinase inhibitor, axitinib.

Conference:

Presenting Author: Del Rivero J

Authors: Del Rivero J, Fojo T, Edgerly M, Pacak K, Figg W,

Keywords: PPGL, pheochromocytoma, paraganglioma, axitinib, TKI, tyrosinase kinase inhibitors,

#3423 MIBG scintigraphy in metastatic neuroblastoma: A retrospective study of 25 cases

Introduction: Meta-iodobenzylguanidine (MIBG) scintigraphy is the first-line functional imaging agent used in neuroblastoma imaging, identifying both the primary tumor and sites of metastatic disease.

Conference:

Presenting Author:

Authors: Ghomari C, Nasri A, Tahraoui Z, Merad S, Medjahedi A,

Keywords: I-MIBG, neuroblastoma, metastasis,

#3421 131I-MIBG scintigraphy in the diagnosis of pheochromocytoma: Retrospective study of 50 cases

Introduction: Pheochromocytoma is a rare tumor of the adrenal medulla. Its exploration with Metaiodobenzylguanidine (MIBG) scintigraphy is one of the current standard diagnostic procedures.

Conference:

Presenting Author:

Authors: Ghomari C, Tahraoui Z, Merad S, Medjahedi A,

Keywords: 131I-MIBG, pheochromocytoma, specificity,

#3285 Somatostatin-receptor scintigraphy in an uncommon neuroendocrine tumor

Introduction: Primary mesenteric neuroendocrine tumors (MNETs) have been rarely reported in the literature and especially their exploration with the somatostatin receptor scintigraphy (SRS) imaging which is a valuable tool for diagnostic, staging and follow-up.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author:

Authors: Ghomari C, Benzerdjeb S, Medjahedi A,

Keywords: mesenteric neuroendocrine tumor, tektrotyd scan, metastases,

#3006 Teratoma with Malignant Transformation: A Case Report of a Neuroendocrine Tumor That Arises from the Bronchial Mucosa in a Mature Cystic Teratoma

Introduction: Mature cystic teratoma (MCT) is the most common type of germ cell tumor in the ovary. A malignant tumor that arises in a pre-existing mature teratoma is called teratoma with malignant transformation (TMT).

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Espinola Benza M

Authors: Espinola Benza M, La Salvia A, Hernandez Sanchez L, Gallardo Gallego R, Suarez Pita D,

Keywords: Mature cystic teratoma, teratoma with malignant transformation, surgical resection,