Abstract Library
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ENETS Abstract Search
#2834 Tumor-Promoting Effects of the Transcriptional Regulator CUX1 in PanNET
Introduction: Previously, we identified CUX1 as mediator of metastatic behaviour and poor differentiation in human insulinomas. CUX1 mediated tumor-promoting functions via enhancing proliferation, resistance to apoptosis and angiogenesis in-vitro and in-vivo.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author: Weißbach J
Authors: Weißbach J, Schmitz R, Haybäck J, Perren A, Blank A,
Keywords: CUX1, RIP1Tag2, DAPK1, Apoptosis, Tumor Progression,
#1780 PD-L1 Is Expressed in a Subset of Pancreatic Neuroendocrine Tumors (pNET)
Introduction: Programmed death 1 (PD-1) is an immune inhibitory receptor expressed on several immune cells, interacting with two ligands, PD-L1 and PD-L2. The former is expressed in many human cancers and is used as a selection criterion for indication of checkpoint inhibitor therapies. PD-L1 is also a potential target for checkpoint inhibitors in pNET therapy, however no data on prevalence of PD-L1 expression and potential associations to clinico-pathologic features is available.
Conference: 14th Annual ENETSConcerence (2017)
Presenting Author: Saganas C
Authors: Saganas C, Blank A, Franzelli M, Marinoni I, Perren A,
Keywords: neuroendocrine, tumors,
Introduction: Chromogranin A (CgA) is the most frequently used biomarker in digestive neuroendocrine neoplasms (DNENs) but its real usefulness is still unclear
Conference: 13th Annual ENETSConcerence (2016)
Presenting Author:
Authors: Merola E, Delle Fave G, Blankenstein O, Wiedenmann B, Pavel M,
Keywords: CgA, clinical usefulness, ≥ 50% increase,
#1230 Ga-68 Somatostatin Receptor PET/CT in the Detection of Insulinoma
Introduction: Presence of somatostatin receptors on beta cells of pancreas is a matter of debate.
Conference: 12th Annual ENETSConcerence (2015)
Presenting Author: Prasad V
Authors: Prasad V, Blankenstein O, Plöckinger U, Pape U, Pascher A,
Keywords: somatostatin receptor PET/CT, Insulinoma,
Introduction: In neuroendocrine tumors (NET) grading and staging are the only routinely performed procedures to judge prognosis. Proliferation index using MIB1 staining has been introduced to assess grading. There are discussions on cut-off definitions, automated counting and inter-observer variability.
Conference: 12th Annual ENETSConcerence (2015)
Presenting Author: Perren A
Authors: Blank A, Wehweck L, Marinoni I, Boos L, Schmitt A,