Abstract Library

#4655 A novel nonpeptide drug conjugate (NDC) for the treatment of somatostatin receptor 2-expressing tumours

Introduction: Somatostatin receptor 2 (SST2) is an established target for the treatment of NETs and potentially other solid tumours.

Conference:

Presenting Author:

Authors: Zhao J, Sturchler E, Yang B, Chen M, Tang Y,

Keywords: somatostatin, solid tumour, drug conjugate, internalisation, cytotoxicity,

#4172 Hormonally characterised NF-PanNETs and their clinicopathological features

Introduction: PanNETs show pronounced hormonal heterogeneity. The expression of certain hormones may associate with functional syndromes, but also with histological and genetic features. However, detailed studies of hormonal patterns in PanNETs correlated to morphological and clinical data are lacking.

Conference:

Presenting Author: Moser E

Authors: Moser E, Ito A, Vogel L, Steiger K, Scheidhauer K,

Keywords: Neuroendocrine Tumor, hormonal expression, subtypes, outcome, transcriptional factors,

#4137 Liquid biopsy as a new tool for the molecular profiling of neuroendocrine neoplasms: The Gustave Roussy experience

Introduction: Molecular profiling (MP) in neuroendocrine neoplasm (NEN) tumor tissue may be useful for precision medicine. Liquid biopsy (LB) is an alternative noninvasive strategy to perform MP.

Conference:

Presenting Author:

Authors: Gagliardi I, Boilève A, Fodil-Cherif S, Moog S, Lamartina L,

Keywords: neuroendocrine tumor, neuroendocrine carcinoma, molecular profile, liquid biopsy, clonal hematopoiesis,

#3895 NGS in G1-G2 pancreatic NETs – Data collection at University Hospital of Verona

Introduction: Pancreatic neuroendocrine tumors (pNETs) are known to have few druggable gene alterations. One possible area of interest concerns the possibility of giving better biological connotations to the >10% subgroup.

Conference:

Presenting Author: Borghesani M

Authors: Borghesani M, Mafficini A, Luchini C, Scarpa A, Milella M,

Keywords: NGS, neuroendocrine, pancreatic,

#3892 Precision medicine in pancreatic MiNEN and other rare pancreatic histologies – A case series from Verona University Hospital

Introduction: Rare tumors of the pancreas represent orphan neoplasms. Better knowledge of their biology will allow more effective treatments to be offered to affected patients.

Conference:

Presenting Author: Trevisani E

Authors: Trevisani E, Mafficini A, Benini L, Borghesani M, Rossi A,

Keywords: Precision medicine, rare pancreas, NGS, gene mutation, MiNEN,