Abstract Library

Welcome to the open-access search for all ENETS abstracts presented at the Annual ENETS Conferences.

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ENETS Abstract Search

#4451 The management of well-differentiated gastroenteropancreatic neuroendocrine tumours in a tertiary centre – The contribution of radionuclide therapy

Introduction: Neuroendocrine tumours represent a heterogenous group of tumours with different locations, whose management is necessary to identify specific parameters that determine the choice of optimal treatment.

Conference:

Presenting Author: Oana Stefania S

Authors: Oana Stefania S, Corin B, Victoria V, Sofia L,

Keywords: GEP-NET, well-differentiated, PRRT, Cromogranine A, Serotonin, RECIST 1.1,

#4077 The importance of pathological sample review in the initial workup study in reference centers: The experience of an ENETS Center of Excellence

Introduction: Neuroendocrine neoplasms (NEN) are complex tumors managed in specialized centers with a multidisciplinary approach. Patients often provide diagnostic studies, including histological material. Pathology department review ensures proper classification, guiding therapies, and potential clinical trial inclusion.

Conference:

Presenting Author:

Authors: Gutierrez Gordo M, Garcia Alvarez A, Hernando J, Landolfi S, Sansano I,

Keywords: Neuroendocrine neoplasm, multidisciplinary, histological review, reference center,

#4060 Interim safety and exploratory efficacy results of a phase 2, randomised, parallel-group study of oral Paltusotine treatment in subjects with carcinoid syndrome

Introduction: Carcinoid Syndrome (CS) is the most common functional NET syndrome. It is characterized by watery diarrhea or cutaneous flushing. Paltusotine is an investigational once-daily, oral, selective SST2 agonist in development for the treatment of acromegaly and CS. Paltusotine has been shown to maintain IGF-1 control at levels similar to injected depot SRLs.

Conference:

Presenting Author:

Authors: Usiskin K, Chauhan A, Mui C, Dillon J, Fan X,

Keywords: oral, paltusotine, carcinoid syndrome, phase II,

#3862 DLL3 determination and immune milieu characterization in Neuroendocrine Neoplasms (NENs)

Introduction: High DLL3 expression in NENs may be used to activate the immune system by redirecting T cells via bispecific T cell engager (BITE) antibodies.

Conference:

Presenting Author:

Authors: Garcia Alvarez A, Serna G, Hernando Cubero J, Napoli S, Carmona Alonso A,

Keywords: Neuroendocrine, DLL3, Immunotherapy,

#2970 Characteristics, Treatments and Inflammatory Biomarkers in Patients (pts) with G3 Gastroenteropancreatic (GEP) Neuroendocrine Neoplasms (NENs)

Introduction: Well-differentiated neuroendocrine tumors G3 (NETsG3) pts have a different biological behavior compared to those with neuroendocrine carcinomas (NECs). Sensitivity to platinum depends on Ki67 and there is no standard second line (2L). Neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) are predictive factors of cancer survival, but with limited evidence in NENs.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Cameselle-Garcia S, Sardo E, Landolfi S, Merino-Casabiel X, Sánchez J,

Keywords: Neuroendocrine Neoplasms, Inflammatory Biomarkers, Gastroenteropancreatic,