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#4441 Gastric neuroendocrine neoplasms in younger patients: A retrospective single-centre study
Introduction: Gastric neuroendocrine neoplasms (gNENs) are rare neoplasms arising from stomach enterochromaffin-like (ECL) cells. Type I gNENs are the most common type, typically indolent and arising in the context of chronic atrophic gastritis (CAG). While type I gNENs are generally diagnosed in pts over 50, their occurrence in younger pts raises concern about the onset of CAG-related complications at an earlier age, potentially affecting tumour growth and clinical outcomes. Young-oriented studies on type I gNETs are still lacking in literature.
Conference:
Presenting Author:
Authors: Romano E, Rinzivillo M, Marasco M, Dell' Unto E, Esposito G,
Keywords: Gastric neuroendocrine neoplasm, Young adults, Chronic Atrophic Gastritis,
Introduction: Gastric neuroendocrine neoplasms (G-NENs), as rare tumours, continue to increase in morbidity and mortality. The specificity of the clinical features of G-NENs has led to a lack of awareness of this disease.
Conference:
Presenting Author:
Keywords: Gastric neuroendocrine neoplasm, Clinicopathologic features, Prognosis,
Introduction: In autoimmune atrophic gastritis (AAG), mucosa morpho-functional changes lead to hypo-achlorhydria, hypergastrinemia, and enterochromaffin-like (ECL) cells proliferation, escalating the risk of type I gastric neuroendocrine neoplasms (gNENs). Longitudinal studies on the AAG-gNENs association are scanty.
Conference:
Presenting Author: Gallo C
Authors: Massironi S, Gallo C, Lahner E, Sciola V, Cavalcoli F,
Keywords: neuroendocrine tumor, atrophic gastritis, autoimmune gastritis, gastrin,
Introduction: The incidence of type I gastric neuroendocrine neoplasms (gNEN) has increased substantially over the past 50 years, although studies evaluating the association with chronic autoimmune atrophic gastritis (CAAG) in the long term have been inconsistent.
Conference:
Presenting Author: Gallo C
Authors: Gallo C, Laffusa A, Elvevi A, Mass S,
Keywords: atrophic gastritis, autoimmune gastritis, gastrin, neuroendocrine tumor,
Introduction: The optimal endoscopic management for Gastric Neuroendocrine Neoplasms (G-NENs) is yet to be determined, and data are limited in the literature.
Conference:
Presenting Author: Lazaridis N
Authors: Lazaridis N, Despott E, Chacchi-Cahuin R, Lemmers A, Rimondi A,