Abstract Library
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ENETS Abstract Search
Introduction: Immunohistochemical expression of synaptophysin (SYN), chromogranin (CgA) and cytokeratin are essential for diagnosis of NENs. Non-NENs, however, may occasionally also express NE-markers and cytokeratin and cause diagnostic difficulties.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author: Kasajim A
Authors: Kasajima A, Konukiewitz B, Schlitter A, Weichert W, Klöppel G,
Keywords: pitfalls, pathology diagnosis,
Introduction: G3 gastroenteropancreatic neuroendocrine tumors (G3 NET) and carcinomas (G3 NEC) differ considerably concerning their biological behavior and patients outcome. Whereas the WHO2017 classification for pancreatic NETs proposes a distinction of both groups using the Ki-67 proliferation marker (Klöppel et al. Reviews and Reports 2017), a useful marker for the subclassification of G3 intestinal NETs have not been recommended until now.
Conference: 15th Annual ENETSConcerence (2018)
Presenting Author: Briest F
Authors: Briest F, Konukiewitz B, Anlauf M, Klöppel G, Grabowski P,
Keywords: gastroenteropancreatic neuroendocrine tumors, GEP-NET, NET G3, NEC G3, Tumor marker, FOXM1, Ki-67, differentiation,
Introduction: The accuracy of the new WHO grading system for neuroendocrine neoplasms has not yet been validated for ileal neuroendocrine tumors (iNETs).
Conference: 9th Annual ENETSConcerence (2012)
Presenting Author:
Authors: Henopp T, Sperveslage J, Anlauf M, Klöppel G, Neumayer B,
Keywords: ileal NET, proliferation, prognosis,
#564 Genetic Alterations in Glucagon Cell Adenomatosis
Introduction: Glucagon cell adenomatosis (GCA) was recently recognized by us as a multifocal neoplastic disease of the endocrine pancreas unrelated to MEN-1. Multiple micro- and a few macrotumors are found on the background of a hyperplasia of glucagon cells. The disease may cause unspecific abdominal symptoms and only rarely a glucagonoma syndrome. Recently a mutation in the glucagon receptor (GCGR) gene was described in one GCA patient.
Conference: 9th Annual ENETSConcerence (2012)
Presenting Author:
Authors: Henopp T, Anlauf M, Biskup S, Klöppel G, Sipos B,
Keywords: glucagon,
#558 MANECs Among Colorectal Signet Ring Cell Carcinomas
Introduction: The mixed adenoneuroendocrine carcinomas (MANEC, WHO 2010) are neoplasms with heterogeneous morphology, whose mixed nature may be difficult to recognize.
Conference: 9th Annual ENETSConcerence (2012)
Presenting Author:
Authors: Hermann G, Yarom N, Konukiewitz B, Sandbank J, Klöppel G,
Keywords: manec, signet ring cell carcinoma, colon, rectum,