Abstract Library

#3287 Utilization of next generation sequencing in NET/NEC management and practice patterns: A prospective survey of global NET specialists

Introduction: Next generation sequencing based somatic tumor mutation as well as germline mutation data is being increasingly used in cancer management. Pan tumor type FDA approval for NTRK fusion, intermediated-high tumor mutation burden and MSI high status has paved way for tissue agnostic molecularly targeted therapies. Utilization of NGS in neuroendocrine tumor (NET) and neuroendocrine carcinoma (NEC) is currently unknown.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author:

Authors: Chauhan A, Munir A, Hernando J, Leeuwaarde R, Zhang P,

Keywords: NGS, NEC, NET,

#2130 Remote Tracking of Symptoms, QoL and Wellbeing within the New Wales NET Service

Introduction: Patients with NETs have worse health-related quality of life (HRQoL) than the general population. Technological advances have significantly increased electronic patient-reported outcome (ePRO) data collection capabilities. There is little longitudinal PRO/ePRO data and limited data on gastrointestinal symptoms, particularly ‘diarrhoea’, in NET patients.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Reynolds M

Authors: Reynolds M, Tucker L, Ankita B, Powell C, Hopps R,

Keywords: Quality of Life, Symptoms, ePRO, Diarrhoea, NET service, Longitudinal Data, CABARET, app,

#1410 Predictive Factors for Survival in Patients with Advanced Small Bowel Neuroendocrine Tumours

Introduction: Tumour grade and hepatic metastases are negative prognostic factors for advanced small bowel neuroendocrine tumours (SBNETs), but data assessing other prognosticators at diagnosis (Dx) are lacking.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: TOUMPANAKIS C

Authors: Toumpanakis C, Vlachou E, Ramakrishnan S, Phillips E, Tuck A,

Keywords: small bowel NETs, prognosis,

#1408 Epidemiological Factors at Diagnosis in a Large Cohort of Patients with Small Bowel Neurondocrine Tumours

Introduction: The incidence of small bowel Neuroendocrine Tumours (SBNETs) has been increasing. Despite previous reports, epidemiological data regarding several clinical factors are limited.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: TOUMPANAKIS C

Authors: Toumpanakis C, Vlachou E, Wilkins D, Tuck A, Phillips E,

Keywords: Small bowel NETs, epidemiology, diagnosis,

#813 Comparison of Manual and Automatic Methods of Ki-67 Proliferation Index for Neuroendocrine Tumors: The Development and Validation of a Novel Digital Pathology Tool (Ki-67Counter)

Introduction: Ki-67 proliferation index is an increasingly important biomarker used to grade neuroendocrine tumors. Manual counting methods are laborious and subject to inter- and intra-observer variability. Digital counting methods hold promise for fast and reproducible indices, however, they are fraught with technical difficulties.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author:

Authors: Neltner J, Su H, Xing F, Rosser J, Cibull M,

Keywords: digital pathology, automated Ki-67 counting, image analysis,