Abstract Library

#4371 Clinical management of oesophageal NEC: A popular based study

Introduction: The clinical research of neuroendocrine carcinoma (NEC) in oesophagus are limited.

Conference:

Presenting Author:

Authors: Cai W, Zhang J, Ge W, Hu H,

Keywords: neuroendocrine carcinoma, oesophagus, clinical practice, survival,

#4231 Analysis of AI-based clinical trial search tool usage reveals motivations of neuroendocrine tumors patients in searching for trials

Introduction: It is challenging to recruit neuroendocrine tumors (NETs) patients to clinical trials. Delays in trial recruitment are detrimental to progress in clinical research. One potential reason for delays is that many patients report not being offered trials.

Conference:

Presenting Author: Mailman J

Authors: Ralic D, Mailman J,

Keywords: AI, patient engagement, clinical research, NET, clinical trials,

#3689 Claudin18.2 expression in gastroenteropancreatic neuroendocrine neoplasms – A clinico-pathologic study

Introduction: Claudin18.2 is a tight junction protein. Currently, the application of Claudin 18.2 antibody in patients has achieved a great efficacy. However, there are still few systematic studies on the expression of Claudin18.2 in gastroenteropancreatic neuroendocrine neoplasms（GEP-NENs).

Conference:

Presenting Author:

Authors: Sun Y, Jiang K, Hu Y, Li J, Lu M,

Keywords: gastroenteropancreatic neuroendocrine neoplasm, claudin18.2, expression,

#3373 Educational learning investigational observational study (ELIOS): A 10-year Italian network to standardize procedures and obtain multicentric clinical research studies

Introduction: Neuroendocrine neoplasms (NEN) are heterogeneous tumors with peculiar biology and rising incidence. Multidisciplinary approach in skilled centers is required to manage these patients. Accurate and complete data are indispensable for high quality epidemiological and clinical research.

Conference:

Presenting Author:

Authors: Modica R, Tafuto S, Riccardi F, Di Sarno A, Rodriquenz M,

Keywords: neuroendocrine, research, network,

#2270 Development of Pre-Clinical NEN Models – Limitations and Opportunities

Introduction: Pre-clinical research in neuroendocrine neoplasia (NEN) has long been impaired by the paucity of NET and NEC cell lines. Furthermore, established models have not been widely available or displayed unusual features (eg. p53 and ras mutations, high proliferation rate).

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Schrader J

Authors: Schrader J, Benten D, Unrau L, Fahl M, Eggers C,

Keywords: cell line,